Document Detail


Fetal bilateral renal agenesis, phocomelia, and single umbilical artery associated with cocaine abuse in early pregnancy.
MedLine Citation:
PMID:  14745934     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Maternal cocaine abuse in pregnancy is associated with complications such as intrauterine growth retardation, abruptio placentae, and preterm delivery. CASE: We report what is, to our knowledge, the first published observation of fetal bilateral renal agenesis associated with a vascular disruption syndrome comprising upper limb reduction defect and a single umbilical artery following maternal cocaine abuse in early pregnancy. CONCLUSIONS: This constellation in a fetus aborted at 18 weeks extends the spectrum of complications possibly associated with cocaine abuse in pregnancy.
Authors:
Maki Kashiwagi; Rabih Chaoui; Thomas Stallmach; Sandra Hürlimann; Urs Lauper; Gundula Hebisch
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Birth defects research. Part A, Clinical and molecular teratology     Volume:  67     ISSN:  1542-0752     ISO Abbreviation:  Birth Defects Res. Part A Clin. Mol. Teratol.     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2004-01-27     Completed Date:  2004-07-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101155107     Medline TA:  Birth Defects Res A Clin Mol Teratol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  951-2     Citation Subset:  IM    
Copyright Information:
Copyright 2003 Wiley-Liss, Inc.
Affiliation:
Department of Obstetrics & Gynecology, Clinic of Obstetrics & Division of Perinatal, Physiology, University of Zurich, Zurich, Switzerland. Maki.Kashiwagi@fhk.usz.ch
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / chemically induced*,  diagnosis*
Adult
Cocaine / toxicity*
Cocaine-Related Disorders*
Congenital Abnormalities
Ectromelia / chemically induced*
Female
Fetus / drug effects
Humans
Kidney / abnormalities*
Male
Maternal Exposure*
Maternal-Fetal Exchange
Pregnancy
Umbilical Arteries / abnormalities*
Chemical
Reg. No./Substance:
50-36-2/Cocaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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