| Fetal bilateral renal agenesis, phocomelia, and single umbilical artery associated with cocaine abuse in early pregnancy. | |
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MedLine Citation:
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PMID: 14745934 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Maternal cocaine abuse in pregnancy is associated with complications such as intrauterine growth retardation, abruptio placentae, and preterm delivery. CASE: We report what is, to our knowledge, the first published observation of fetal bilateral renal agenesis associated with a vascular disruption syndrome comprising upper limb reduction defect and a single umbilical artery following maternal cocaine abuse in early pregnancy. CONCLUSIONS: This constellation in a fetus aborted at 18 weeks extends the spectrum of complications possibly associated with cocaine abuse in pregnancy. |
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Authors:
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Maki Kashiwagi; Rabih Chaoui; Thomas Stallmach; Sandra Hürlimann; Urs Lauper; Gundula Hebisch |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Birth defects research. Part A, Clinical and molecular teratology Volume: 67 ISSN: 1542-0752 ISO Abbreviation: Birth Defects Res. Part A Clin. Mol. Teratol. Publication Date: 2003 Nov |
Date Detail:
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Created Date: 2004-01-27 Completed Date: 2004-07-12 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 101155107 Medline TA: Birth Defects Res A Clin Mol Teratol Country: United States |
Other Details:
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Languages: eng Pagination: 951-2 Citation Subset: IM |
Copyright Information:
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Copyright 2003 Wiley-Liss, Inc. |
Affiliation:
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Department of Obstetrics & Gynecology, Clinic of Obstetrics & Division of Perinatal, Physiology, University of Zurich, Zurich, Switzerland. Maki.Kashiwagi@fhk.usz.ch |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abnormalities, Multiple
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chemically induced*,
diagnosis* Adult Cocaine / toxicity* Cocaine-Related Disorders* Congenital Abnormalities Ectromelia / chemically induced* Female Fetus / drug effects Humans Kidney / abnormalities* Male Maternal Exposure* Maternal-Fetal Exchange Pregnancy Umbilical Arteries / abnormalities* |
| Chemical | |
Reg. No./Substance:
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50-36-2/Cocaine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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