| Fetal arrhythmias: natural history and management. | |
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MedLine Citation:
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PMID: 15653224 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim was to delineate the significance and natural history of fetal arrhythmias and provide information about their management. A cohort of 114 infants with fetal arrhythmias detected during prenatal ultrasound (US) screening were studied. All subjects underwent echocardiography and were treated as clinically indicated. Postnatal outcome was obtained in 100% of infants until 1 year of age. The incidence of fetal arrhythmias was 0.3%. Among the 87 fetuses with atrial extrasystoles, 2.3% developed supraventricular tachycardia (SVT) in utero. Of the 10 SVT cases, only five required antiarrhythmic therapy in utero with digoxin and propafenone, which successfully restored sinus rhythm in 100% of fetuses, both nonhydropic and hydropic. Sinus bradycardia was associated with structural anomalies in 5 of 6 patients and only 2 of 4 fetuses with atrioventricular block survived. It is concluded that prognosis is good for most fetal tachyarrhythmias, whereas it is less favorable for bradyarrhythmias. |
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Authors:
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Patrizia Vergani; Eloisa Mariani; Elena Ciriello; Anna Locatelli; Nicola Strobelt; Mariella Galli; Alessandro Ghidini |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Ultrasound in medicine & biology Volume: 31 ISSN: 0301-5629 ISO Abbreviation: Ultrasound Med Biol Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2005-01-17 Completed Date: 2005-05-09 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0410553 Medline TA: Ultrasound Med Biol Country: England |
Other Details:
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Languages: eng Pagination: 1-6 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, University of Milano-Bicocca, Monza, Italy. pvergani@yahoo.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Arrhythmia Agents
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therapeutic use Arrhythmias, Cardiac / drug therapy, etiology, ultrasonography* Cohort Studies Digoxin / therapeutic use Fetal Diseases / drug therapy, ultrasonography* Fetal Therapies / methods* Heart Defects, Congenital / complications Humans Prognosis Tachycardia, Ectopic Atrial / drug therapy, ultrasonography Ultrasonography, Prenatal / methods* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Arrhythmia Agents; 20830-75-5/Digoxin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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