Document Detail


Fetal arrhythmias: natural history and management.
MedLine Citation:
PMID:  15653224     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim was to delineate the significance and natural history of fetal arrhythmias and provide information about their management. A cohort of 114 infants with fetal arrhythmias detected during prenatal ultrasound (US) screening were studied. All subjects underwent echocardiography and were treated as clinically indicated. Postnatal outcome was obtained in 100% of infants until 1 year of age. The incidence of fetal arrhythmias was 0.3%. Among the 87 fetuses with atrial extrasystoles, 2.3% developed supraventricular tachycardia (SVT) in utero. Of the 10 SVT cases, only five required antiarrhythmic therapy in utero with digoxin and propafenone, which successfully restored sinus rhythm in 100% of fetuses, both nonhydropic and hydropic. Sinus bradycardia was associated with structural anomalies in 5 of 6 patients and only 2 of 4 fetuses with atrioventricular block survived. It is concluded that prognosis is good for most fetal tachyarrhythmias, whereas it is less favorable for bradyarrhythmias.
Authors:
Patrizia Vergani; Eloisa Mariani; Elena Ciriello; Anna Locatelli; Nicola Strobelt; Mariella Galli; Alessandro Ghidini
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ultrasound in medicine & biology     Volume:  31     ISSN:  0301-5629     ISO Abbreviation:  Ultrasound Med Biol     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-01-17     Completed Date:  2005-05-09     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0410553     Medline TA:  Ultrasound Med Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1-6     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, University of Milano-Bicocca, Monza, Italy. pvergani@yahoo.it
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MeSH Terms
Descriptor/Qualifier:
Anti-Arrhythmia Agents / therapeutic use
Arrhythmias, Cardiac / drug therapy,  etiology,  ultrasonography*
Cohort Studies
Digoxin / therapeutic use
Fetal Diseases / drug therapy,  ultrasonography*
Fetal Therapies / methods*
Heart Defects, Congenital / complications
Humans
Prognosis
Tachycardia, Ectopic Atrial / drug therapy,  ultrasonography
Ultrasonography, Prenatal / methods*
Chemical
Reg. No./Substance:
0/Anti-Arrhythmia Agents; 20830-75-5/Digoxin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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