Document Detail

Fetal anemia: new technologies.
MedLine Citation:
PMID:  15017345     Owner:  NLM     Status:  MEDLINE    
PURPOSE OF REVIEW: The purpose of this review is to summarize recently published studies on noninvasive diagnosis of fetal anemia in order to give recommendations for the use of these new tools. RECENT FINDINGS: Red cell alloimmunization remains one of the most common causes of fetal anemia. Amniocentesis and cordocentesis have been used for many years to diagnose fetal anemia due to red cell aloimmunization. These techniques, however, are invasive and many complications are associated with their use. Noninvasive diagnosis of fetal anemia has been performed with Doppler ultrasonography. Based on robust data, several authors recommend the use of middle cerebral artery peak systolic velocity in the management of fetuses at risk for anemia because of red cell alloimmunization. This Doppler parameter can also diagnose fetal anemia due to other conditions. SUMMARY: Middle cerebral artery peak systolic velocity appears to be the best test for the noninvasive diagnosis of fetal anemia. It is important to emphasize that training of sonographers and sonologists is the 'conditio sine qua non' for the correct sampling of the middle cerebral artery.
Maria Segata; Giancarlo Mari
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Current opinion in obstetrics & gynecology     Volume:  16     ISSN:  1040-872X     ISO Abbreviation:  Curr. Opin. Obstet. Gynecol.     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-03-12     Completed Date:  2004-10-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9007264     Medline TA:  Curr Opin Obstet Gynecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  153-8     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of Cincinnati, Cincinnati, Ohio 45267, USA.
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MeSH Terms
Anemia / diagnosis*,  etiology
Blood Flow Velocity
Fetal Diseases / diagnosis*,  etiology
Fetus / physiopathology
Middle Cerebral Artery / embryology,  physiopathology*
Rh Isoimmunization / complications,  diagnosis
Ultrasonography, Doppler
Ultrasonography, Prenatal

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