Document Detail


Fetal alcohol syndrome.
MedLine Citation:
PMID:  7264859     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Significant alcohol ingestion during pregnancy can cause a spectrum of malformation of various degrees of severity in offspring. The full expression of "fetal alcohol syndrome" includes reduced growth, facial anomalies, and mental retardation. Affected infants are usually of near-term gestation, but small in weight and length. They continue to exhibit decreased growth postnatally. Mental retardation appears to be related to the degree of dysmorphic severity of appearance. It is primarily caused by central nervous system pathology rather than social environment. The most prevalent ophthalmologic finding in our series of a short horizontal palpebral fissure appears to be due primarily to a marked increased in intercanthal distances between the medial canthi (primary telecanthus) and to less extent mild displacement of the lateral canthi. Ptosis, often asymmetric, was noted in a number of patients. Comitant convergent strabismus was present in about 50% of our cases; a few had amblyopia. An important observation was the frequent and often high degree of myopia in these children. Low-incidence anomalies include corneal opacities (Peters anomaly in one), cataract, tortuosity of retinal vessels, and long eyelashes. Our findings plus many observations in the literature establish that children with fetal alcohol syndrome are at considerable risk for a variety of eye problems.
Authors:
M Miller; J Israel; J Cuttone
Related Documents :
16754549 - Alcohol consumption, smoking and breastfeeding in the first six months after delivery.
3226379 - The interactive effects of alcohol and cocaine on maternal and fetal toxicity in the lo...
2304039 - Maternal and fetal effects of heroin addiction during pregnancy.
9366129 - Attitudes and knowledge about drinking: relationships with drinking behavior among preg...
23574709 - Surgical abortion prior to 7 weeks of gestation: release date march 2013 sfp guideline ...
9684559 - The biopersistence and pathogenicity of man-made vitreous fibres after short- and long-...
24354539 - Hypoproteinemia in the second trimester among patients with preeclampsia prior to the o...
9021389 - Inhibin in extra-embryonic coelomic and amniotic fluids and maternal serum in early pre...
3706429 - Hypertensive diseases of pregnancy and parity.
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of pediatric ophthalmology and strabismus     Volume:  18     ISSN:  0191-3913     ISO Abbreviation:  J Pediatr Ophthalmol Strabismus     Publication Date:    1981 Jul-Aug
Date Detail:
Created Date:  1981-10-25     Completed Date:  1981-10-25     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7901143     Medline TA:  J Pediatr Ophthalmol Strabismus     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  6-15     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Child
Child, Preschool
Diseases in Twins
Eye Diseases / etiology*
Eyelids / abnormalities*
Female
Fetal Alcohol Syndrome / complications*
Humans
Infant
Infant, Newborn
Male
Myopia / etiology
Pregnancy
Strabismus / etiology
Grant Support
ID/Acronym/Agency:
DE-02872/DE/NIDCR NIH HHS; EY1792/EY/NEI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Development of the eyeball during fetal life.
Next Document:  Validation of a projective measure of aggression-anxiety for five-year-old boys.