| Fetal alcohol syndrome: an assessment of the field. | |
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MedLine Citation:
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PMID: 15956764 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fetal exposure to alcohol is the major known cause of mental retardation in the Western world. For more than half of the 20th century, the placenta was widely believed to be an effective barrier against environmental agents. The discovery that offspring of pregnant women who were exposed to German measles or administered thalidomide were often malformed raised awareness that teratogens could be any environmental agent, including viruses and drugs, that caused abnormal development. Alcohol was not identified as a teratogen until the 1970s. Fetal exposure to alcohol can cause fetal alcohol syndrome (FAS), which is characterized by specific physical traits and central nervous system dysfunctions. The development of animal model systems has facilitated our study of the effects of fetal alcohol exposure and the elucidation of the mechanisms involved in alcohol-induced abnormal development. Despite our current understanding of the effects of fetal alcohol exposure, the occurrence of FAS and associated fetal alcohol spectrum disorders is still widespread and the associated health-care costs are staggering. This symposium provides an up-to-date analysis of fetal exposure to alcohol and FAS. It is directed not only to investigators working in the field but to a diverse group of scientists working in the biological and biomedical fields to stimulate cross-disciplinary awareness, interest, and collaboration. |
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Authors:
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James R West; Charles A Blake |
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Publication Detail:
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Type: Congresses |
Journal Detail:
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Title: Experimental biology and medicine (Maywood, N.J.) Volume: 230 ISSN: 1535-3702 ISO Abbreviation: Exp. Biol. Med. (Maywood) Publication Date: 2005 Jun |
Date Detail:
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Created Date: 2005-06-15 Completed Date: 2005-07-18 Revised Date: 2005-10-25 |
Medline Journal Info:
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Nlm Unique ID: 100973463 Medline TA: Exp Biol Med (Maywood) Country: United States |
Other Details:
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Languages: eng Pagination: 354-6 Citation Subset: IM |
Affiliation:
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Department of Human Anatomy and Medical Neurobiology, College of Medicine, The Texas A&M University System Health Science Center, College Station, Texas 77843-1114, USA. jrwest@medicine.tamhsc.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Alcohol Drinking
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adverse effects* Animals Disease Models, Animal Female Fetal Alcohol Syndrome / etiology*, prevention & control Humans Mental Retardation / etiology Pregnancy Prenatal Exposure Delayed Effects* Teratology |
| Comments/Corrections | |
Comment In:
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Exp Biol Med (Maywood). 2005 Jun;230(6):407-12
[PMID:
15956770
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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