| Fetal alcohol spectrum disorders and their persisting sequelae in adult life. | |
| | |
MedLine Citation:
|
PMID: 19623288 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
INTRODUCTION: The present review describes the different variants of Fetal Alcohol Spectrum Disorders (FASD) as a consequence of maternal alcohol abuse during pregnancy. According to international findings, some 3000 to 4000 affected newborns may be expected annually in Germany. Detection of these individuals in clinical practice is insufficient. METHOD: Selective review of the literature and report of own findings based on longitudinal studies. RESULTS: Key features of FASD are short stature, microcephaly, various dysmorphic features, in severe cases amongst others consisting of congenital heart disease and dysplasias of the skeleton and urogenital system, varying degrees of developmental delay including mental retardation, and a positive history of maternal alcohol abuse during pregnancy. Longitudinal studies in young adulthood show that independent of the severity of FASD the key features remain associated with limitations of an independent life-style. DISCUSSION: Pathogenesis of FASD is not sufficiently clear and there is no causal treatment. Thus, besides prevention and information, early diagnosis, installation of fostering or adoption, and intensive psychosocial care including selection of appropriate schooling, occupational counselling and supportive care in adulthood are mandatory. |
| | |
Authors:
|
Hans-Ludwig Spohr; Hans-Christoph Steinhausen |
Related Documents
:
|
15385858 - Women and omega-3 fatty acids. 17984398 - Causal inferences regarding prenatal alcohol exposure and childhood externalizing probl... 4033128 - A cross-ethnic comparison of reasons given for using alcohol, not using alcohol or ceas... 17875358 - Prenatal alcohol exposure, cyp17 gene polymorphisms and fetal growth restriction. 7148388 - Geographical pattern of death rates from multiple sclerosis in france. an analysis of 4... 22216148 - Choriodecidual group b streptococcal inoculation induces fetal lung injury without intr... |
Publication Detail:
|
Type: Journal Article Date: 2008-10-10 |
Journal Detail:
|
Title: Deutsches Ärzteblatt international Volume: 105 ISSN: 1866-0452 ISO Abbreviation: Dtsch Arztebl Int Publication Date: 2008 Oct |
Date Detail:
|
Created Date: 2009-07-22 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101475967 Medline TA: Dtsch Arztebl Int Country: Germany |
Other Details:
|
Languages: eng Pagination: 693-8 Citation Subset: - |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Mastocytosis: a disease of the hematopoietic stem cell.
Next Document: Vocal cord dysfunction: an important differential diagnosis of bronchial asthma.