Document Detail

The fetal vermis, pons and brainstem: normal longitudinal development as shown by dedicated neurosonography.
MedLine Citation:
PMID:  23211125     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To describe the normal appearance and the growth of the fetal vermis, pons and midline brainstem by ultrasound from 18 weeks of gestation to term in order to produce developmental nomograms.
METHODS: Serial ultrasound examinations of the fetal brain were performed in 21 fetuses between 18 and 39 weeks of gestation every two weeks. A total of 173 examinations were done, 8.2 ± 5.2 examinations per fetus. A mid-sagittal plain of the brain was obtained either by transvaginal or transabdominal sonography. Antero-posterior, cranio-caudal diameters, and surface area of the pons and the vermis were measured. The surface area of the brain stem was also measured. Nomograms were produced according to Royston and Wright.
RESULTS: The pons, vermis and brain stem grow in a linear fashion throughout pregnancy. The growth pattern correlates well with gestational age, biparietal diameter, head circumference and the cerebellar transverse diameter.
CONCLUSIONS: We have provided nomograms for assessment of the fetal brainstem. The present information supplies tools for the accurate identification of fetal mid-hindbrain anomalies providing a solid basis for a multidisciplinary approach, management and counseling of these conditions.
Shimon Ginath; Tally Lerman-Sagie; Karina Haratz Krajden; Dorit Lev; Bina Cohen-Sacher; Jacob Bar; Gustavo Malinger
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Publication Detail:
Type:  Journal Article     Date:  2013-01-13
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  26     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-04-22     Completed Date:  2014-01-27     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  757-62     Citation Subset:  IM    
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MeSH Terms
Brain Stem / embryology,  ultrasonography*
Cerebellum / embryology,  ultrasonography
Fetal Development*
Pons / embryology,  ultrasonography*
Reference Values
Ultrasonography, Prenatal*

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