| Fetal Longitudinal Myocardial Function Assessment by Anatomic M-Mode. | |
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MedLine Citation:
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PMID: 22613840 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Aim: To evaluate the feasibility of offline anatomic M-mode (AMM) to study fetal atrioventricular annulus long-axis displacement (LAD) and compare its performance against real-time conventional M-mode (MM). Material and Methods: Paired AMM and MM LAD studies were recorded prospectively in 54 fetuses, and performance was compared. Insonation angles were less than 30° in all but 4 cases. The overall feasibility of AMM was tested in a composite total sample of 91 normal singleton pregnancies (median gestational age 23(+6) weeks, range 12-36). AMM LAD was measured by placement of a virtual M-mode line on digitally stored raw data of fetal 4-chamber video loops. We studied annulus LAD at the lateral mitral (left ventricle; LV), proximal mitral (intraventricular septum; IVS), and lateral tricuspid (right ventricle; RV) myocardial segments. We compared LAD and its regression with gestational age measured using both methods in paired studies and AMM in the whole cohort. Results: Annulus LAD was measured using AMM, in all cases and segments, irrespective of cardiac axis alignment to the ultrasound beam. Good correlation existed between AMM and MM (RV r = 0.901, LV r = 0.899, IVS r = 0.815, p < 0.001). AMM recorded higher LAD values than MM in RV [mean 6.17 (SD 1.46) vs. 5.82 (SD 1.74) mm, p = 0.002] and LV [mean 4.18 (SD 1.11) vs. 3.98 (SD 1.12), p = 0.007]. Both methods showed LAD in RV > LV > IVS and a significant gestational increase in LAD values in all segments (p < 0.001) Conclusions: AMM permits offline evaluation of fetal longitudinal myocardial function in routinely obtained 2D fetal heart images with similar values to conventional MM in paired studies recorded <30°. |
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Authors:
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Ioannis Germanakis; Spyridon Pepes; Stavros Sifakis; Helena Gardiner |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-5-17 |
Journal Detail:
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Title: Fetal diagnosis and therapy Volume: - ISSN: 1421-9964 ISO Abbreviation: - Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-5-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9107463 Medline TA: Fetal Diagn Ther Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 S. Karger AG, Basel. |
Affiliation:
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Pediatric Cardiology Unit, Department of Pediatrics, University Hospital Heraklion, Heraklion, Greece. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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