Document Detail

Fetal Diagnosis of Left-Ventricular Noncompaction Cardiomyopathy in Identical Twins With Discordant Congenital Heart Disease.
MedLine Citation:
PMID:  22695766     Owner:  NLM     Status:  Publisher    
Left-ventricular noncompaction (LVNC) is characterized by prominent myocardial trabeculae with deep intratrabecular recesses. Associated with ventricular dysfunction, LVNC can present in isolation or in conjunction with structural heart defects (i.e., "nonisolated" LVNC). Although it was once considered to be difficult and unreliable, successful detection of this condition by way of fetal echocardiography has been well documented. We present what is to our knowledge the first prenatal diagnosis of LVNC in monochorionic-monozygotic twins. Nonisolated LVNC was identified in twins A and B at 23 weeks' gestation. A noncompaction-to-compaction ratio >2 was documented in both cases. Discordance for congenital heart disease was observed in the twins: Twin A presented with pulmonary atresia with an intact ventricular septum, critical tricuspid stenosis, and severe right-ventricular hypoplasia, whereas twin B presented with mild mitral valve dysplasia. Despite an initially complicated postnatal course for twin A, this case shows that it is feasible to achieve good outcomes with accurate prenatal detection and aggressive postnatal management.
Cheryl A Vinograd; Shubhika Srivastava; Laurie E Panesar
Related Documents :
7300416 - An improved method of topical cardiac hypothermia.
16320926 - L-arginine effects on myocardial stress in cardiac surgery: preliminary results.
8906176 - Normothermic ischemia in coronary revascularization.
3931596 - The effect of adding mannitol or albumin to a crystalloid cardioplegic solution: a pros...
24772416 - Proteomic profiling of the dystrophin-deficient mdx phenocopy of dystrophinopathy-assoc...
2321536 - Transmural ventricular activation during consecutive cycles of sustained ventricular ta...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-15
Journal Detail:
Title:  Pediatric cardiology     Volume:  -     ISSN:  1432-1971     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003849     Medline TA:  Pediatr Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Pediatrics, Stony Brook University School of Medicine, Stony Brook Long Island Children's Hospital, Stony Brook, HSC-T-11, Room 040, New York, 11794, USA,
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Portal and Sinusoidal Fibrosis are Common on Liver Biopsy After Fontan Surgery.
Next Document:  Deep-eutectic solvents playing multiple roles in the synthesis of polymers and related materials.