Document Detail

Fetal alcohol syndrome, Tourette syndrome, and hyperactivity in nine adopted children.
MedLine Citation:
PMID:  20610121     Owner:  NLM     Status:  MEDLINE    
Much attention has been paid in recent years to the role of prenatal exposure to alcohol. Fetal alcohol syndrome is one of the most severe afflictions resulting from such exposure. The present report documents the cases of adopted children diagnosed with fetal alcohol syndrome who developed both Tourette syndrome and attention deficit-hyperactivity disorder. Out of a population of 138 adopted children with behavior issues whose clinical histories were reviewed retrospectively, 9 children (6.5%) presented this constellation. Epidemiologic data, clinical data, neurologic examination findings, complementary testing, and developmental data were recorded. All nine patients studied had initial psychomotor retardation, despite the frequent case of subsequent intelligence quotient normalization. From a behavioral perspective, half of the cases presented obsessive-compulsive disorder and problems with social relations. Aggressive behavior was common. These cases also presented a high degree of severity of both tics and hyperactivity. The most common drug treatment was methylphenidate. This constellation of fetal alcohol syndrome, Tourette syndrome, and attention deficit-hyperactivity disorder is scantly reported in the literature and is likely underdiagnosed. This particular constellation poses its own prognosis and requires its own treatment.
Daniel Martín Fernández-Mayoralas; Alberto Fernández-Jaén; Nuria Muñoz-Jareño; Beatriz Calleja Pérez; Rafael Arroyo-González
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric neurology     Volume:  43     ISSN:  1873-5150     ISO Abbreviation:  Pediatr. Neurol.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-08     Completed Date:  2011-01-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508183     Medline TA:  Pediatr Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  110-6     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Department of Neuropediatrics, Hospital Quirón, Pozuelo de Alarcón (Madrid), Spain.
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MeSH Terms
Adoption / psychology*
Attention Deficit Disorder with Hyperactivity* / diagnosis,  psychology
Child, Preschool
Fetal Alcohol Syndrome* / diagnosis,  psychology
Neuropsychological Tests
Prenatal Exposure Delayed Effects*
Psychiatric Status Rating Scales
Retrospective Studies
Tourette Syndrome* / diagnosis,  psychology

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