Document Detail


Fertility and its complications in a patient with salt losing congenital adrenal hyperplasia.
MedLine Citation:
PMID:  10392354     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A report is made concerning fertility and its complications in a patient with salt losing congenital adrenal hyperplasia. Fertility with a successful outcome of pregnancy has rarely been reported in women with salt losing congenital adrenal hyperplasia. Problems which have been identified in the past include non-compliance, poor endocrine follow up, secondary polycystic ovarian disease with menstrual irregularity, anovulation and problems related to sexual function. There has been only one report in the literature of a woman with salt losing congenital adrenal hyperplasia who has had two pregnancies with live births. There has been no previous report of subsequent problems with neonatal management of these children. This case highlights some of the long term hazards of management of salt losing congenital adrenal hyperplasia and reports for the first time neonatal complications possibly consequent upon prenatal maternal therapy.
Authors:
M Zacharin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric endocrinology & metabolism : JPEM     Volume:  12     ISSN:  0334-018X     ISO Abbreviation:  J. Pediatr. Endocrinol. Metab.     Publication Date:    1999 Jan-Feb
Date Detail:
Created Date:  1999-09-20     Completed Date:  1999-09-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9508900     Medline TA:  J Pediatr Endocrinol Metab     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  89-94     Citation Subset:  IM    
Affiliation:
Department of Endocrinology and Diabetes, Royal Children's Hospital, Parkville, Victoria, Australia.
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MeSH Terms
Descriptor/Qualifier:
17-alpha-Hydroxyprogesterone / blood
Adrenal Glands / drug effects
Adrenal Hyperplasia, Congenital / blood,  drug therapy*
Adult
Androstenedione / blood
Female
Fludrocortisone / adverse effects,  therapeutic use
Humans
Hydrocortisone / adverse effects,  therapeutic use
Infant, Newborn
Infant, Newborn, Diseases / chemically induced
Pregnancy
Pregnancy Complications / etiology*
Prenatal Exposure Delayed Effects
Chemical
Reg. No./Substance:
127-31-1/Fludrocortisone; 50-23-7/Hydrocortisone; 63-05-8/Androstenedione; 68-96-2/17-alpha-Hydroxyprogesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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