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Fertility, infertility and thrombophilia.
MedLine Citation:
PMID:  21879823     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Hypercoagulation has been reported in some studies to be associated with reproductive failures, such as unexplained infertility, IVF implantation failure and recurrent fetal losses. Many pregnancy-related disorders have been interpreted as consequences of impaired microvascular function and might be viewed as a mild form of venous thromboembolic disease. In the absence of clinical guidelines, there is a need for an evidence base regarding thrombophilic screening and antithrombotic therapy in cases of reproductive failure. This article will focus on the controversial effect of congenital and acquired thrombophilia on human fertility, and will review the English literature for relevant studies identified by searching PubMed(®) results between January 1966-November 2010 using the key words: 'thrombophilia', 'fertility' and 'infertility'.
Authors:
Amir Kuperman; Pierpaolo Di Micco; Benjamin Brenner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Women's health (London, England)     Volume:  7     ISSN:  1745-5065     ISO Abbreviation:  Womens Health (Lond Engl)     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-09-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101271249     Medline TA:  Womens Health (Lond Engl)     Country:  England    
Other Details:
Languages:  eng     Pagination:  545-53     Citation Subset:  IM    
Affiliation:
The Ruth & Bruce Rappaport Faculty of Medicine, Technion, Efron Street, PO Box 9649, Bat Galim, Haifa 31096, Israel; Thrombosis & Hemostasis Service & Pediatric Hematology Clinic, Western Galilee Hospital, PO Box 21, Nahariya 22100, Israel.
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