Document Detail


Ferritin immunohistochemical study on pontine nuclei from infants with pontosubicular neuron necrosis.
MedLine Citation:
PMID:  7762757     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Immunohistochemical ferritin staining was performed on pontine nuclei of the brains of 17 infants with pontosubicular neuron necrosis (PSN), aged 23 to 42 weeks of gestation. Ferritin-positive cells were increased in cases of karyorrhexis with spongy changes and gliosis, but not in those of selective karyorrhexis. Ferritin-positive cells were more increased in the cases with extensive karyorrhectic neurons. Iron may be released to the damaged pontine tissue as a catalyst and microglia may play an important role in the repair of the tissue.
Authors:
H Ozawa; A Nishida; T Mito; S Takashima
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Brain & development     Volume:  17     ISSN:  0387-7604     ISO Abbreviation:  Brain Dev.     Publication Date:    1995 Jan-Feb
Date Detail:
Created Date:  1995-06-26     Completed Date:  1995-06-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7909235     Medline TA:  Brain Dev     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  20-3     Citation Subset:  IM    
Affiliation:
Department of Mental Retardation and Birth Defect Research, National Center of Neurology and Psychiatry, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Astrocytes / chemistry
Ferritins / analysis*
Glial Fibrillary Acidic Protein / analysis
Humans
Immunohistochemistry
Infant
Microglia / chemistry
Necrosis
Neurons / chemistry*,  pathology
Oligodendroglia / chemistry
Pons / chemistry*,  pathology*
Ricin
Chemical
Reg. No./Substance:
0/Glial Fibrillary Acidic Protein; 9007-73-2/Ferritins; 9009-86-3/Ricin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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