Document Detail

Ferritin, a faithful reflection of iron deficiency in IUD wearers with mild vaginal spotting.
MedLine Citation:
PMID:  1872195     Owner:  NLM     Status:  MEDLINE    
In a group of 34 parous women, mean age 36.2 years, fitted with a copper-releasing IUD (18 with Multiload 250 or 375, and 16 with Nova T) the following parameters were assessed before and 4 months after the device insertion: hemoglobin, hematocrit, iron and ferritin. The only complaint of all patients was the shortening of the menstrual cycle, from 28 +/- 1.2 to 26.8 +/- 1.9 days, and the longer period of days with vaginal spotting (from 3.9 +/- 1.1 to 7.1 +2- 1.0 days). While Hb, HTC and iron remained within normal limits, there was a drastic fall in ferritin, from 24.2 +/- 16.4 to 9.3 +/- 8.7 ng/ml (p less than 0.01), a sign of iron deficiency anemia. Periodic ferritin assessment and iron treatment, if needed, should be the first choice. Removal of the IUD is recommended only when ferritin remains low after antifibrinolytic, prostaglandin synthetase inhibitors, and iron therapy.
M Blum; J Ariel; D Zacharowitch
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in contraception : the official journal of the Society for the Advancement of Contraception     Volume:  7     ISSN:  0267-4874     ISO Abbreviation:  Adv Contracept     Publication Date:  1991 Mar 
Date Detail:
Created Date:  1991-09-13     Completed Date:  1991-09-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8607435     Medline TA:  Adv Contracept     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  39-42     Citation Subset:  IM    
Family Planning Clinic, Mishmar Hayarden, Kupat Holim, Dan District, Israel.
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MeSH Terms
Ferritins / biosynthesis*
Hemoglobins / analysis
Intrauterine Devices, Copper*
Iron / blood
Menstrual Cycle
Middle Aged
Reg. No./Substance:
0/Hemoglobins; 7439-89-6/Iron; 9007-73-2/Ferritins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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