Document Detail


Fentanyl-induced bradykinesia and rigidity after deep brain stimulation in a patient with Parkinson disease.
MedLine Citation:
PMID:  19471184     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 58-year-old man with advanced Parkinson disease underwent battery replacement for a deep brain stimulator and experienced severe bradykinesia and rigidity postoperatively for 36 hours. The patient was administered fentanyl as an anesthetic during the procedure and as an analgesic periodically during the day after surgery. The severe bradykinesia and rigidity persisted despite reactivation of the deep brain stimulator and immediate reinstitution of Parkinson disease medications, but resolved completely several hours after discontinuation of fentanyl.
Authors:
Theresa A Zesiewicz; Robert A Hauser; Alan Freeman; Kelly L Sullivan; Amber M Miller; Tariq Halim
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical neuropharmacology     Volume:  32     ISSN:  1537-162X     ISO Abbreviation:  Clin Neuropharmacol     Publication Date:    2009 Jan-Feb
Date Detail:
Created Date:  2009-05-27     Completed Date:  2009-09-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7607910     Medline TA:  Clin Neuropharmacol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  48-50     Citation Subset:  IM    
Affiliation:
Parkinson's Disease and Movement Disorders Center, Department of Neurology, University of South Florida, Tampa, 33612, USA. tzesiewi@hsc.usf.edu
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MeSH Terms
Descriptor/Qualifier:
Analgesics, Opioid / adverse effects*
Deep Brain Stimulation / adverse effects*
Fentanyl / adverse effects*
Humans
Hypokinesia / chemically induced*
Male
Middle Aged
Muscle Rigidity / etiology*
Parkinson Disease / therapy*
Chemical
Reg. No./Substance:
0/Analgesics, Opioid; 437-38-7/Fentanyl

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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