Document Detail

Fenestrated occluders for treatment of ASD in elderly patients with pulmonary hypertension and/or right heart failure.
MedLine Citation:
PMID:  18086135     Owner:  NLM     Status:  MEDLINE    
Atrial septal defect (ASD) occlusion in adult patients with advanced age and left or right heart diastolic or systolic heart failure and in patients with pulmonary arterial hypertension bears a considerable risk of deterioration of heart failure. Therefore, we conducted this feasibility trial in 15 ASD patients with pulmonary hypertension and/or right heart failure using a fenestrated Amplatzer septal occluder (AGA Medical Corporation, Golden Valley, MN), allowing an overflow of blood in both directions in case of univentricular diastolic or systolic heart failure. In all patients, the device could be implanted without complications. All symptomatic patients showed an improvement in the New York Heart Association (NYHA) class, and no right or left heart decompensation occurred. On echocardiography, right ventricular end diastolic dimension (RVEDD) and pulmonary artery pressure (PAP) decreased significantly, whereas left ventricular end diastolic dimension (LVEDD) increased. Our series of 15 patients with fenestrated ASD occlusion shows that high-risk ASD occlusion can safely be accomplished with excellent clinical results and without complications by a fenestrated occluder.
Leonhard Bruch; Anne Winkelmann; Steffen Sonntag; Franziska Scherf; Sascha Rux; Marc O Grad; Franz X Kleber
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Publication Detail:
Type:  Journal Article     Date:  2007-12-11
Journal Detail:
Title:  Journal of interventional cardiology     Volume:  21     ISSN:  0896-4327     ISO Abbreviation:  J Interv Cardiol     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-02-07     Completed Date:  2008-05-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8907826     Medline TA:  J Interv Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  44-9     Citation Subset:  IM    
From the Department of Internal Medicine/Cardiology, Unfallkrankenhaus Berlin Academic Teaching Hospital, Berlin, Germany.
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MeSH Terms
Age Factors
Feasibility Studies
Heart Failure / physiopathology,  surgery*,  ultrasonography
Heart Septal Defects, Atrial / physiopathology,  surgery*
Heart Ventricles / physiopathology,  ultrasonography
Hypertension, Pulmonary / physiopathology,  surgery*,  ultrasonography
Middle Aged
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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