| Fenestrated and branched endografts for the treatment of thoracoabdominal aortic aneurysms: a systematic review. | |
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MedLine Citation:
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PMID: 20426638 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To offer a critical review of the current literature on the use of fenestrated and branched stent-grafts in patients with thoracoabdominal aortic aneurysms (TAAA). METHODS: A thorough search of the English-language literature published between January 2000 and September 2009 identified reports of endovascular procedures using fenestrated and/or branched endografts as the intended repair strategy in patients with TAAA. Studies were selected based on specific inclusion criteria: (1) >3 high-risk patients with preoperative diagnosis of TAAA, (2) the intended treatment strategy was an endovascular repair using a fenestrated or branched endograft or both, and (3) patient demographics and outcome data (technical success rate, 30-day mortality, and follow-up length) were clearly stated. From 47 articles initially identified, 7 studies were included in the statistical analysis encompassing 155 patients (mean age 74.4 years, range 41-86) with TAAA averaging 69.2 mm in diameter. The mean follow-up was 11.8 months, and the majority of patients had Crawford type IV aneurysms. Outcome measures of eligible studies were tabulated and then analyzed cumulatively. RESULTS: Technical success was achieved in 94.2% (n = 146) of the 155 patients. Twenty-three (18.4%) primary endoleaks were reported. The 30-day mortality was 7.1% (n = 11), while the 1-year survival rate was 82.6% (n = 128). Three (1.9%) patients developed permanent paraplegia and 2 (1.3%) developed permanent paraparesis; renal failure was reported in 9 (5.8%). Overall follow-up mortality was 16.1% (n = 25). CONCLUSION: Endovascular treatment with fenestrated or/and branched stent-grafts is a new therapeutic option with encouraging results for patients considered unfit for conventional open repair. However, prolonged follow-up studies are needed in order to draw robust conclusions. |
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Authors:
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Chris N Bakoyiannis; Konstantinos P Economopoulos; Sotirios Georgopoulos; Chris Klonaris; Maria Shialarou; Marina Kafeza; Efstathios Papalambros |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists Volume: 17 ISSN: 1545-1550 ISO Abbreviation: J. Endovasc. Ther. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-29 Completed Date: 2010-08-12 Revised Date: 2010-10-20 |
Medline Journal Info:
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Nlm Unique ID: 100896915 Medline TA: J Endovasc Ther Country: United States |
Other Details:
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Languages: eng Pagination: 201-9 Citation Subset: IM |
Affiliation:
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First Department of Surgery, Vascular Department, University of Athens, "Laiko" General Hospital, Athens, Greece. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty* Aortic Aneurysm, Thoracic / etiology, pathology, therapy* Blood Vessel Prosthesis* Blood Vessel Prosthesis Implantation* Humans Patient Selection Prosthesis Design Prosthesis Fitting Stents* Treatment Outcome |
| Comments/Corrections | |
Comment In:
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J Endovasc Ther. 2010 Apr;17(2):212-5
[PMID:
20426640
]
J Endovasc Ther. 2010 Oct;17(5):673-4; author reply 674-5 [PMID: 20939730 ] J Endovasc Ther. 2010 Apr;17(2):210-1 [PMID: 20426639 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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