Document Detail

Femoral nerve block using ropivacaine 0.025%, 0.05% and 0.1%: effects on the rehabilitation programme following total knee arthroplasty: a pilot study.
MedLine Citation:
PMID:  18540926     Owner:  NLM     Status:  MEDLINE    
Femoral nerve blockade is recommended for analgesia following total knee arthroplasty. Following implementation of this type of postoperative analgesia in our hospital we found that active mobilization the day after surgery, may be difficult due to insufficient quadriceps muscle strength. We therefore designed a pilot study comparing the effect of ropivacaine 0.1%, 0.05% or 0.025% on the patient's postoperative rehabilitation and analgesia. Three groups of 12 patients received bolus doses of ropivacaine via their femoral nerve catheters for postoperative analgesia. The ability to actively mobilize, quadriceps muscle strength, pain VAS-scores and patient's satisfaction were measured during in the first three postoperative days. There were no significant differences in the patient's ability to actively mobilize and the pain VAS-scores. The overall satisfaction of the patients with the pain treatment was significantly better (p = 0.049) in the 0.1% compared with the 0.025% group. This pilot-study demonstrated no advantage associated with the use of a ropivacaine concentration less than 0.1%.
J J Paauwe; B J Thomassen; J Weterings; E van Rossum; M E Ausems
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2008-06-06
Journal Detail:
Title:  Anaesthesia     Volume:  63     ISSN:  1365-2044     ISO Abbreviation:  Anaesthesia     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-08-13     Completed Date:  2008-09-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  England    
Other Details:
Languages:  eng     Pagination:  948-53     Citation Subset:  AIM; IM    
Department of Anaesthesiology, Maasland Hospital, Orbis medisch en Zorgconcern, MB, Sittard, the Netherlands.
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MeSH Terms
Amides / administration & dosage*
Anesthetics, Local / administration & dosage*
Arthroplasty, Replacement, Knee / rehabilitation*
Dose-Response Relationship, Drug
Double-Blind Method
Drug Administration Schedule
Early Ambulation / methods
Femoral Nerve
Knee Joint / physiopathology
Middle Aged
Muscle Strength / drug effects
Muscle, Skeletal / physiopathology
Nerve Block / methods*
Pain Measurement / methods
Pain, Postoperative / prevention & control*
Patient Satisfaction
Pilot Projects
Postoperative Care / methods
Range of Motion, Articular
Reg. No./Substance:
0/Amides; 0/Anesthetics, Local; 84057-95-4/ropivacaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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