Document Detail

Femoral-infrapopliteal bypass with prosthetic grafts.
MedLine Citation:
PMID:  10520926     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Patients who require prosthetic infrapopliteal of the lower extremity have historically had dismal long-term results. This study examined the outcome of patients undergoing femoral-distal arterial bypass with expanded polytetrafluoroethylene (ePTFE) grafts. METHODS: Femoral to infrapopliteal artery bypasses with ePTFE performed between 1990 and 1997 were reviewed. Graft patency, limb salvage, and survival rates were calculated by actuarial analysis. Different anastomotic adjuncts (direct end-to-side anastomosis, vein patch anastomosis, and arteriovenous fistula [AVF] anastomosis) were compared with the log-rank test. RESULTS: Seventy-four femoral-infrapopliteal bypasses with ePTFE were performed in 67 patients for limb salvage. At 24 months the primary patency, assisted primary patency, and secondary patency rates were 40% +/- 10% (SEMAI), 48% +/- 11%, and 52% +/- 11%, respectively. Limb salvage was successful in 62 % +/- 10% of the bypasses at 24 months. Forty-six percent of the bypasses were performed with an AVF; 35% were performed with direct end-to-side anastomosis, and 19% were performed with a vein patch anastomosis. Apparent trends in favor of the AVF group did not attain statistical significance with 24-month patency rates of 65% +/- 19%, 44% +/- 16%, and 35% +/- 20%, respectively, in the 3 subgroups. Limb salvage rates were similar (64% +/- 17%, 56% +/- 15%, and 76% +/- 22%, respectively) at 24 months. CONCLUSIONS: Patency and limb salvage rates are sufficient to justify the use of ePTFE grafts in infrapopliteal bypass when adequate autogenous material is unavailable.
M J Eagleton; K Ouriel; C Shortell; R M Green
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgery     Volume:  126     ISSN:  0039-6060     ISO Abbreviation:  Surgery     Publication Date:  1999 Oct 
Date Detail:
Created Date:  1999-10-25     Completed Date:  1999-10-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417347     Medline TA:  Surgery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  759-64; discussion 764-5     Citation Subset:  AIM; IM    
University of Rochester Medical Center, Section of Vascular Surgery, NY 14642, USA.
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MeSH Terms
Aged, 80 and over
Anastomosis, Surgical
Arterial Occlusive Diseases / mortality,  surgery*
Blood Vessel Prosthesis*
Femoral Artery / surgery*
Graft Occlusion, Vascular
Middle Aged
Polytetrafluoroethylene / therapeutic use*
Popliteal Artery / surgery*
Retrospective Studies
Survival Analysis
Treatment Outcome
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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