| Female-specific issues in multiple sclerosis. | |
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MedLine Citation:
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PMID: 18505361 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Complex neuroendocrine mechanisms regulating the immune response can be recognized in all autoimmune diseases. Such mechanisms develop through endocrine loops and feedback processes along the hypothalamus-pituitary-gonads axis and the hypothalamus-pituitary- adrenal gland axis. Females are not only more susceptible to autoimmune diseases, but are also more exposed to relevant variations of hormonal levels that physiologically go along with women's life. This paper reviews female-specific issues in multiple sclerosis and how treatments must be considered accordingly. In particular, aspects related to puberty, menses, fertility, pregnancy, lactation and menopause are considered in addition to epidemiological and clinical issues. |
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Authors:
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Angelo Ghezzi; Mauro Zaffaroni |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Expert review of neurotherapeutics Volume: 8 ISSN: 1744-8360 ISO Abbreviation: Expert Rev Neurother Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-05-28 Completed Date: 2008-07-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101129944 Medline TA: Expert Rev Neurother Country: England |
Other Details:
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Languages: eng Pagination: 969-77 Citation Subset: IM |
Affiliation:
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Centro Studi Sclerosi Multipla Via Pastori, 4, I-21013 Gallarate, Italy. centro.sm@aogallarate.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Autoimmune Diseases
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complications*,
diagnosis,
therapy* Female Humans Multiple Sclerosis / complications*, diagnosis, therapy* Women's Health* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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