Document Detail


Female pseudohermaphroditism in a neonate born to a mother with polycystic ovarian disease.
MedLine Citation:
PMID:  3773077     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A newborn with female pseudohermaphroditism (profound masculinization of the external genitalia and preservation of the internal female genitalia) is presented. During pregnancy progressive hirsutism was noted in the mother, and polycystic ovaries were found at cesarean section. The serum testosterone level in the cord blood was elevated markedly (1,232 ng./dl). After birth the serum testosterone levels of the mother and newborn decreased dramatically. Over-all it appears that the polycystic ovaries were the source of the excessive androgen secretion that caused maternal and fetal masculinization during the pregnancy.
Authors:
M Bilowus; V Abbassi; M D Gibbons
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of urology     Volume:  136     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  1986 Nov 
Date Detail:
Created Date:  1986-11-24     Completed Date:  1986-11-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1098-100     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Female
Fetal Blood / analysis
Humans
Infant, Newborn
Polycystic Ovary Syndrome / blood,  complications*
Pregnancy
Pregnancy Complications / blood*
Pseudohermaphroditism / etiology*
Testosterone / blood*
Chemical
Reg. No./Substance:
58-22-0/Testosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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