Document Detail

Female and male chronic obstructive pulmonary disease patients with severe dyspnea do not profit less from pulmonary rehabilitation.
MedLine Citation:
PMID:  18714736     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Pulmonary rehabilitation (PR) is an established component of COPD management. The lack of exercise performance improvement (EPI) in severely dyspnoeic patients (Medical Research Council [MRC] score 5) has been questioned. The data on the gender impact on EPI after PR remain scarce. OBJECTIVES: The impact of dyspnea severity on PR outcomes was investigated and a question was raised whether severe dyspnea at training onset limits the profit from PR in COPD patients. Additionally, the impact of gender on PR results was analyzed. PATIENTS AND METHODS: 263 consecutive COPD patients underwent outpatient PR. Exercise capacity was assessed by the incremental shuttle walking test (SWT) and dyspnea with the MRC dyspnea score at inclusion (preSWT, preMRC) and at the end of PR (postSWT, postMRC). The data were analyzed in groups according to preMRC. The grade of improvement (deltaSWT, deltaSWT% and deltaMRC) was compared between groups. The influence of gender was analyzed in 138 men and 125 women. RESULTS: A significant absolute increase in SWT and a decrease in MRC score were shown in all groups and for both sexes (p < 0.05) with no significant intergroup differences (p > 0.05). deltaSWT% rose significantly with preMRC score and exceeded the values of a clinically important increase (exception: group 2 with preMRC score 2). No significant differences between men and women were observed (deltaMRC: -0.6 vs. -0.7, deltaSWT: 66.7 vs. 56.0 m, deltaSWT%: 63.7 vs. 58.1%, p > 0.05, respectively). CONCLUSIONS: Patients with severe dyspnea did not benefit less from PR. Gender did not influence PR outcome in this study.
Maria Karolina Lizak; Sally Singh; Szymon Lubina; Marian Zembala
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Polskie Archiwum Medycyny Wewn?trznej     Volume:  118     ISSN:  0032-3772     ISO Abbreviation:  Pol. Arch. Med. Wewn.     Publication Date:    2008 Jul-Aug
Date Detail:
Created Date:  2008-08-21     Completed Date:  2008-10-15     Revised Date:  2010-04-01    
Medline Journal Info:
Nlm Unique ID:  0401225     Medline TA:  Pol Arch Med Wewn     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  413-8     Citation Subset:  IM    
Silesian Centre for Heart Disease, Zabrze, Poland.
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MeSH Terms
Aged, 80 and over
Analysis of Variance
Dyspnea / etiology*,  rehabilitation*
Exercise Therapy / methods*
Follow-Up Studies
Forced Expiratory Volume
Middle Aged
Prospective Studies
Pulmonary Disease, Chronic Obstructive / complications,  rehabilitation*
Severity of Illness Index
Sex Factors
Treatment Outcome
Vital Capacity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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