Document Detail

Felty syndrome complicating juvenile rheumatoid arthritis.
MedLine Citation:
PMID:  9787332     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To describe a case of Felty syndrome (FS) in a child with (JRA) and review the previous literature on this rare entity.
METHODS: Review of clinical data including results of serial blood counts, bone marrow aspirate, human leukocyte antigen (HLA)-typing, and abdominal sonography.
RESULTS: Serial blood counts over 2 years revealed persistent leukopenia and thrombocytopenia. Bone marrow aspirate showed normal trilineage hematopoiesis, abdominal sonography demonstrated an enlarged spleen, but normal liver and portal circulation. HLA-typing was most significant for positivity of the DR 1 allele.
CONCLUSION: This is only the third child, and the first preadolescent, to be reported with FS complicating juvenile rheumatoid arthritis. This condition needs to be considered in the differential diagnosis when leukopenia, thrombocytopenia, or both develop in patients with JRA.
B J Bloom; P Smith; A J Alario
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric hematology/oncology     Volume:  20     ISSN:  1077-4114     ISO Abbreviation:  J. Pediatr. Hematol. Oncol.     Publication Date:    1998 Sep-Oct
Date Detail:
Created Date:  1998-11-10     Completed Date:  1998-11-10     Revised Date:  2011-10-06    
Medline Journal Info:
Nlm Unique ID:  9505928     Medline TA:  J Pediatr Hematol Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  511-3     Citation Subset:  IM    
Department of Pediatrics, Hasbro Children's Hospital, Providence, Rhode Island 02903, USA.
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MeSH Terms
Arthritis, Juvenile Rheumatoid*
Child, Preschool
Felty's Syndrome*

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