Document Detail


Feline systemic hypertension: Classification and pathogenesis.
MedLine Citation:
PMID:  21215946     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PRACTICAL RELEVANCE: the increased availability of indirect blood pressure monitoring devices in clinical practice over the past decade has highlighted the significance of systemic hypertension in the feline population. Without routine monitoring and appropriate intervention, cats with undiagnosed systemic hypertension may first be presented with sudden-onset blindness as a consequence of either hyphaema or retinal detachment.
CLINICAL CHALLENGES: the primary aim in the early diagnosis and treatment of systemic hypertension is prevention of hypertensive target organ damage (with respect to the eye, kidney, cardiovascular and central nervous systems, in particular). A prerequisite is a knowledge of the pathophysiological mechanisms and disease conditions that may contribute to the development of hypertension. This allows the clinician to determine those cases in which blood pressure assessment and longitudinal monitoring is essential and can assist in determining appropriate therapeutic strategies for control of blood pressure. Recent studies have also begun to explore the relationship that systemic hypertension may have with proteinuria and the progression of kidney disease.
PATIENT GROUP: the geriatric cat appears most susceptible to the development of systemic hypertension, and monitoring of systolic blood pressure is often advocated as part of a routine health screen in cats over 9-12 years old. Consideration must also be given to cats suspected of having an underlying disease such as chronic kidney disease or hyperthyroidism, or which are receiving therapeutic agents, irrespective of their age.
EVIDENCE BASE: much of our understanding of the pathogenesis of feline hypertension is extrapolated from studies performed in experimental animal models or in human patients, and interspecies differences are often poorly understood.
Authors:
Rosanne E Jepson
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of feline medicine and surgery     Volume:  13     ISSN:  1532-2750     ISO Abbreviation:  J. Feline Med. Surg.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-10     Completed Date:  2011-02-16     Revised Date:  2013-11-06    
Medline Journal Info:
Nlm Unique ID:  100897329     Medline TA:  J Feline Med Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  25-34     Citation Subset:  IM    
Affiliation:
Department of Veterinary Clinical Services, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herifordshire AL9 7TA, UK. rjepson@rvc.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Animals
Cat Diseases / classification*,  etiology*,  physiopathology
Cats
Humans
Hypertension / classification,  etiology,  physiopathology,  veterinary*
Hyperthyroidism / complications,  therapy,  veterinary
Male

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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