Document Detail

Feline attractant, cis,trans-nepetalactone: metabolism in the domestic cat.
MedLine Citation:
PMID:  5770619     Owner:  NLM     Status:  MEDLINE    
cis,trans-Nepetalactone, the biologically active component of catnip, was force-fed to the domestic cat. When the (14)C-labeled compound was fed, 86 to 94 percent of the radioactivity was recovered in the urine, 1 to 2 percent was found in the feces, and 1 to 12 percent was collected as carbon dioxide. The major (50 to 75 percent) metabolite was alpha-nepetalinic acid, which was excreted in the urine together with small amounts of dihydronepetalactone, unchanged cis,-trans-nepetalactone, and several unidentified compounds. No marked physiological or histological eflects were observed when 20 to 80 milligrams of cis, trans-nepetalactone was administered orally. This is the first report on the metabolism of a mammalian attractant.
G R Waller; G H Price; E D Mitchell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Science (New York, N.Y.)     Volume:  164     ISSN:  0036-8075     ISO Abbreviation:  Science     Publication Date:  1969 Jun 
Date Detail:
Created Date:  1969-07-03     Completed Date:  1969-07-03     Revised Date:  2011-12-07    
Medline Journal Info:
Nlm Unique ID:  0404511     Medline TA:  Science     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1281-2     Citation Subset:  IM    
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MeSH Terms
Animal Feed
Animal Nutritional Physiological Phenomena
Animals, Domestic
Carbon Isotopes
Chromatography, Thin Layer
Lactones / metabolism*
Terpenes / metabolism*
Reg. No./Substance:
0/Carbon Isotopes; 0/Lactones; 0/Terpenes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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