Document Detail


Feline primary hyperaldosteronism.
MedLine Citation:
PMID:  20219494     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Primary hyperaldosteronism (PHA) is being recognized more frequently in cats. Usual hallmarks of the disease include hypokalemia and systemic hypertension. Ultrasound frequently detects an abnormality in the affected adrenal gland. Diagnosis is based on increased plasma or serum aldosterone concentrations, particularly in the face of hypokalemia and low renin activity (when measurement is available). Cats with PHA have good prognoses with surgical excision of tumor-bearing adrenal glands. Medical management can stabilize patients for many months. The reported incidence is likely to increase as practitioners become more aware of the condition and diagnose it earlier in the disease course. If veterinarians choose to use humans as an experimental model, PHA should be considered a differential for cats with hypertension of unknown cause or that is refractory to treatment. Using hypokalemia as a definitive criterion in screening for PHA may result in late-stage diagnosis and underrecognition of incidence of PHA in the hypertensive population.
Authors:
Rhonda L Schulman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Veterinary clinics of North America. Small animal practice     Volume:  40     ISSN:  1878-1306     ISO Abbreviation:  Vet. Clin. North Am. Small Anim. Pract.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-11     Completed Date:  2010-06-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7809942     Medline TA:  Vet Clin North Am Small Anim Pract     Country:  United States    
Other Details:
Languages:  eng     Pagination:  353-9     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Affiliation:
Animal Specialty Group, 4641 Colorado Boulevard, Los Angeles, CA 90039, USA. rhondaschulman@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Aging
Aldosterone / metabolism
Animals
Cat Diseases / diagnosis*,  pathology
Cats
Hyperaldosteronism / diagnosis,  pathology,  veterinary*
Chemical
Reg. No./Substance:
52-39-1/Aldosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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