Document Detail

Feeding of very low birth weight infants born to HCMV-seropositive mothers in Germany, Austria and Switzerland.
MedLine Citation:
PMID:  20670309     Owner:  NLM     Status:  MEDLINE    
AIM:   To evaluate the enteral feeding practice of preterm infants <32 weeks (W) gestational age (GA) or <1500 g birth weight (BW) from human cytomegalovirus (HCMV)-seropositive mothers in Germany, Austria and Switzerland.
METHODS:   This prospective cross-sectional study included all neonatal units (NU) admitting preterm infants <32W or <1500g BW in Germany, Austria and Switzerland. In June and July 2009, an anonymized questionnaire was sent via e-mail, asking whether mothers of the above patients were screened for HCMV, and about the enteral feeding protocol for preterm infants <32W GA or <1500g BW from HCMV-seropositive mothers.
RESULTS:  During the study period, 58.6% of the questionnaires (123/210) from Germany, 50% (13/26) from Austria and 50% (6/12) from Switzerland were returned, yielding a total of 6232 preterm infants for analysis. Formula was given to the mentioned preterm infants in 28.5% (35/123) of the German NUs but not in Austria or Switzerland. Untreated breast milk was given in 66.6% (4/6) of the Swiss, 14.6% (18/123) of the German and no Austrian NU. Long-term pasteurized breast milk was given in 32.5% (40/123) of the German and 38.5% (5/13) of the Austrian NUs, but not in Switzerland. Short-term pasteurized breast milk was given only in 5.7% (7/123) of German NUs. Freeze-thawed breast milk was given in Germany (4.9%; 6/123), Austria (61.5%; 8/13) and Switzerland (16.7%; 1/6).
CONCLUSION:   Preterm infants <32W GA or <1500g BW born to HCMV-seropositive mothers are fed according to different regimes in German-speaking countries. About 28.5% of the German VLBW-infants receive formula, which is not recommended.
Horst Buxmann; Maike Falk; Rangmar Goelz; Klaus Hamprecht; Christian F Poets; Rolf L Schloesser
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  99     ISSN:  1651-2227     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-02     Completed Date:  2011-01-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  1819-23     Citation Subset:  IM    
Copyright Information:
© 2010 The Author(s)/Journal Compilation © 2010 Foundation Acta Paediatrica.
Department of Neonatology, University Children's Hospital of Frankfurt/Main, Frankfurt, Germany.
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MeSH Terms
Clinical Protocols
Cross-Sectional Studies
Cytomegalovirus Infections / diagnosis,  prevention & control,  transmission*
Enteral Nutrition / methods*
Gestational Age
Infant Formula / statistics & numerical data*
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / prevention & control*
Infant, Very Low Birth Weight*
Infectious Disease Transmission, Vertical / prevention & control*
Intensive Care Units, Neonatal
Milk, Human* / chemistry,  virology
Practice Guidelines as Topic
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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