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Feeding Tolerance of Preterm Infants Appropriate for Gestational Age (AGA) as Compared to those Small For Gestational Age (SGA).
MedLine Citation:
PMID:  23131136     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Preterm infants are often considered too unstable to be fed enterally so they are exposed to complications related to a prolonged enteral fasting. Our study aims to compare feeding tolerance of AGA versus SGA infants and to evaluate which perinatal factors affect feeding tolerance (measured as time to achieve full enteral feeding, FEF). Inborn infants with a gestational age (GA) less than 32 weeks, born from January 2006 to December 2010, were eligible to this study. We enrolled 310 infants. The time to FEF was longer for SGA infants than for AGA, while a longer GA was associated to a reduced time to FEF. A protective effect was observed for antenatal steroids, while Apgar score below 7, the administration of inotrops or caffeine, the occurrence of sepsis or NEC, and the presence of PDA were associated to a longer time to FEF. When evaluated jointly with a multivariate analysis, GA (p<0.0001), antenatal steroids prophylaxis (p=0.002), SGA (p<0.0001), and occurrence of NEC (p=0.0002) proved to have independent prognostic impact on the time to FEF. Feeding tolerance is better as GA increases, and worsen in SGA infants. Antenatal steroids reduce the time to FEF and the time between minimal enteral feeding (MEF) and FEF.
Authors:
Valentina Bozzetti; Giuseppe Paterlini; Paola Delorenzo; Valeria Meroni; Diego Gazzolo; Frank Van Bel; Gerard Ha Visser; Maria Grazia Valsecchi; Paolo E Tagliabue
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-6
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Neonatal Intensive Care Unit, MBBM Foundation, San Gerardo Hospital, Monza, Italy.
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