Document Detail

Feeding practices and patent ductus arteriosus ligation preferences-are they related?
MedLine Citation:
PMID:  20225172     Owner:  NLM     Status:  MEDLINE    
We hypothesized that there is a significant relationship between a neonatologist's belief that feedings must be stopped in the presence of a patent ductus arteriosus (PDA) and his or her willingness to ligate a PDA. We administered the same survey questionnaire to two separate populations of neonatologists to assess their beliefs regarding PDA treatment practices. Although >90% of U.S. and non-U.S. neonatologists reported that they would ligate a PDA when infants with birth weights <900 g required mechanical ventilation (and indomethacin was contraindicated or had failed to close the PDA), U.S. neonatologists reported that they were significantly more likely to ligate a PDA when less respiratory support was required. U.S. neonatologists were also more likely to stop feedings when a PDA was present. The reported likelihood that a neonatologist would ligate a PDA in infants who did not require mechanical ventilation was significantly increased if the neonatologist believed that feedings had to be stopped because of the PDA. After controlling for the belief that "feedings must be stopped in the presence of a PDA," the significant difference between U.S. and non-U.S. neonatologists, in their reported desire to ligate infants who did not require mechanical ventilation, was no longer present.
Nami Jhaveri; Roger F Soll; Ronald I Clyman
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2010-03-11
Journal Detail:
Title:  American journal of perinatology     Volume:  27     ISSN:  1098-8785     ISO Abbreviation:  Am J Perinatol     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-12     Completed Date:  2010-12-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  667-74     Citation Subset:  IM    
Copyright Information:
Copyright Thieme Medical Publishers.
Cardiovascular Research Institute and Department of Pediatrics, University of California-San Francisco, San Francisco, CA 94143-0544, USA.
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MeSH Terms
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Birth Weight
Ductus Arteriosus, Patent / physiopathology,  therapy*
Enteral Nutrition*
Indomethacin / therapeutic use
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / physiopathology,  therapy*
Respiration, Artificial
United States
Grant Support
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 53-86-1/Indomethacin

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