Document Detail

Feeding frequency and appetite in lean and obese prepubertal children.
MedLine Citation:
PMID:  20847731     Owner:  NLM     Status:  MEDLINE    
To determine the effect of feeding frequency on appetite in normal weight (NW) and obese (OB) prepubertal children, we carried out a prospective, randomized interventional study of 18 NW and 17 OB children ages 6-10. Children received three or five feedings in random order on separate days. Total calories, carbohydrate, protein, and fat composition on each day were equal. Two hours following the last feeding, children were offered ice cream ad lib. The major outcome variable was kilocalories ice cream consumed. A visual analog scale to assess fullness was also administered before consumption of ice cream. We observed that OB children consumed 73.0 ± 37.4 kcal more after five feedings than after three feedings whereas the NW children consumed 47.1 ± 27.8 kcal less. There was significant interaction between meal pattern and weight group indicating that this change in ice cream consumption differed significantly between groups (P = 0.014 by two-factor analysis). Ice cream intake/kg was less in OB compared to NW subjects (P = 0.012). Fullness ratings before ice cream did not differ by meal pattern or weight group. However, pre-ice cream fullness predicted ice cream intake in NW but not OB children. In summary, OB and NW children differed in appetite response to meal frequency. Our data suggest that: (i) satiety in OB children is related more to proximity of calories (larger supper) than to antecedent distribution of calories and; (ii) NW children may be more prone to restrict intake based on subjective fullness.
Rinku Mehra; Eva Tsalikian; Catherine A Chenard; M Bridget Zimmerman; William I Sivitz
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2010-09-16
Journal Detail:
Title:  Obesity (Silver Spring, Md.)     Volume:  19     ISSN:  1930-739X     ISO Abbreviation:  Obesity (Silver Spring)     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-24     Completed Date:  2011-10-04     Revised Date:  2012-08-13    
Medline Journal Info:
Nlm Unique ID:  101264860     Medline TA:  Obesity (Silver Spring)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  560-7     Citation Subset:  IM    
Department of Pediatrics, Division of Pediatric Endocrinology, The University of Iowa, Iowa City, Iowa, USA.
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MeSH Terms
Dietary Sucrose / administration & dosage
Energy Intake*
Feeding Behavior*
Ice Cream
Obesity / physiopathology*
Pain Measurement
Prospective Studies
Reference Values
Grant Support
Reg. No./Substance:
0/Dietary Sucrose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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