| Federated web-accessible clinical data management within an extensible neuroimaging database. | |
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MedLine Citation:
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PMID: 20567938 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Managing vast datasets collected throughout multiple clinical imaging communities has become critical with the ever increasing and diverse nature of datasets. Development of data management infrastructure is further complicated by technical and experimental advances that drive modifications to existing protocols and acquisition of new types of research data to be incorporated into existing data management systems. In this paper, an extensible data management system for clinical neuroimaging studies is introduced: The Human Clinical Imaging Database (HID) and Toolkit. The database schema is constructed to support the storage of new data types without changes to the underlying schema. The complex infrastructure allows management of experiment data, such as image protocol and behavioral task parameters, as well as subject-specific data, including demographics, clinical assessments, and behavioral task performance metrics. Of significant interest, embedded clinical data entry and management tools enhance both consistency of data reporting and automatic entry of data into the database. The Clinical Assessment Layout Manager (CALM) allows users to create on-line data entry forms for use within and across sites, through which data is pulled into the underlying database via the generic clinical assessment management engine (GAME). Importantly, the system is designed to operate in a distributed environment, serving both human users and client applications in a service-oriented manner. Querying capabilities use a built-in multi-database parallel query builder/result combiner, allowing web-accessible queries within and across multiple federated databases. The system along with its documentation is open-source and available from the Neuroimaging Informatics Tools and Resource Clearinghouse (NITRC) site. |
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Authors:
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I Burak Ozyurt; David B Keator; Dingying Wei; Christine Fennema-Notestine; Karen R Pease; Jeremy Bockholt; Jeffrey S Grethe |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Neuroinformatics Volume: 8 ISSN: 1559-0089 ISO Abbreviation: Neuroinformatics Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101142069 Medline TA: Neuroinformatics Country: United States |
Other Details:
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Languages: eng Pagination: 231-49 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, University of California at San Diego, San Diego, CA, USA. iozyurt@ucsd.edu |
Export Citation:
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Descriptor/Qualifier:
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| Grant Support | |
ID/Acronym/Agency:
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1 U24 RR021992/RR/NCRR NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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