| Features and outcomes in utero and after birth of fetuses with myocardial disease. | |
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MedLine Citation:
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PMID: 20976307 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Objectives. Ninety-one fetuses with dilated or hypertrophic cardiomyopathy (DCM, HCM) and myocarditis were studied. Results. Group 1 "DCM" included 19 fetuses: 13 with hydrops (FH) and 5 with associated extracardiac anomalies (ECAs) (15.8%). Group 2 "Myocarditis" included twelve fetuses, having 11 with FH. Group 3 "HCM" included sixty fetuses: 26 had associated ECAs, 17 had maternal diabetes, and 17 were "idiopathic"; however, in one case, a metabolic disorder was found postnatally, and 4 had familiarity for HCM. Outcomes. Ten cases opted for termination of pregnancy. Two cases with DCM and 1 with HCM were lost at follow-up. Out of the cases that continued pregnancy, with known follow-up, mortality was 68.75% in Group 1, 63.6% in Group 2, and 31.3% in Group 3 (the majority with severe ECAs). Surviving cases with DCM and myocarditis improved, 2 with HCM worsened, 6 remained stable, and 26 improved or normalized. Conclusions. Our data show more severe prognosis in DCM and myocarditis and forms with severe associated ECAs. |
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Authors:
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Vlasta Fesslova; Maurizio Mongiovì; Salvatore Pipitone; Jelena Brankovic; Laura Villa |
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Publication Detail:
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Type: Journal Article Date: 2010-10-03 |
Journal Detail:
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Title: International journal of pediatrics Volume: 2010 ISSN: 1687-9759 ISO Abbreviation: Int J Pediatr Publication Date: 2010 |
Date Detail:
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Created Date: 2010-10-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101517077 Medline TA: Int J Pediatr Country: Egypt |
Other Details:
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Languages: eng Pagination: 628451 Citation Subset: - |
Affiliation:
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Center of Fetal Cardiology, Policlinico San Donato IRCCS, Via Morandi 30, San Donato Milanese, 20097 Milan, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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