Document Detail

Features of Urrets-Zavalia Syndrome After Descemet Stripping Automated Endothelial Keratoplasty.
MedLine Citation:
PMID:  22960674     Owner:  NLM     Status:  Publisher    
PURPOSE:: To report a case series of pupil abnormalities consistent with features of Urrets-Zavalia syndrome (UZS) after Descemet stripping automated endothelial keratoplasty (DSAEK) for corneal edema secondary to corneal endothelial cell dysfunction. METHODS:: Retrospective chart analysis of subjects who developed UZS after DSAEK at the University of Texas Southwestern Medical Center. RESULTS:: We present a series of 7 eyes with features consistent with UZS, after undergoing DSAEK. Elevated intraocular pressures (IOP) were noted in the early postoperative period in all cases. Five of 7 had graft dislocation in the postoperative period and required rebubbling or repeat DSAEK to obtain a well-apposed graft. Patients were followed for 3 to 14 months and showed improvement in visual acuity and IOP, but fixed dilated pupils persisted. CONCLUSION:: A fixed irregular or dilated pupil is a rare complication that can be associated with DSAEK surgery. Patients with an elevated IOP and complicated postoperative course seem to be at greater risk for developing iris ischemia and pupil abnormalities consistent with the diagnosis of UZS.
Didar S Anwar; Claire Y Chu; Pawan Prasher; Robert W Bowman; V Vinod Mootha
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-6
Journal Detail:
Title:  Cornea     Volume:  -     ISSN:  1536-4798     ISO Abbreviation:  Cornea     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8216186     Medline TA:  Cornea     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, TX.
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