Document Detail


Features of ST segment and T-wave in exercise-induced myocardial ischemia evaluated with multichannel magnetocardiography.
MedLine Citation:
PMID:  12108575     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND AIM: Magnetocardiography (MCG) is a novel, non-contact mapping technique to record cardiac magnetic field. We evaluated MCG criteria for myocardial ischemia in stress testing. METHODS: Multichannel MCG over frontal chest was performed in 44 patients with coronary artery disease (CAD) and 26 healthy controls during supine bicycle exercise test. Of the 44 patients 16 had anterior, 15 posterior, and 13 inferior ischemia documented by coronary angiography and exercise thallium scintigraphy. ST amplitude, ST slope, T-wave amplitude, and ST-T integral were measured. The optimal sites for detecting the ischemia-induced changes on MCG were sought. The orientation of the magnetic field was also determined. RESULTS: The optimal sites for the decrease of ST slope, ST amplitude, T-wave amplitude, and ST-T integral were over the abdomen. The reciprocal increase of these parameters was found over the left parasternal area. The optimal sites were approximately the same for all patient groups. In single-vessel disease patients without previous myocardial infarction (MI), ST slope increase and ST elevation performed the best (area under the receiver operating characteristic curve 92% and 90%, respectively). In post-MI patients with triple-vessel disease the decrease of T-wave amplitude and ST slope performed the best (area under curve 91%, for both). The magnetic field orientation at ST segment performed equally well as the other ST parameters. In stepwise logistic regression analysis, by use of the presence of CAD as the dependent parameter, ST slope increase and ST peak gradient orientation entered the model. CONCLUSIONS: Various ST segment and T-wave parameters detect ischemia in MCG. ST amplitude performs especially well in non-MI patients with less severe CAD. In advanced CAD late development of T-wave amplitude might be more sensitive to ischemia than ST amplitude.
Authors:
Helena Hänninen; Panu Takala; Petri Korhonen; Lasse Oikarinen; Markku Mäkijärvi; Jukka Nenonen; Toivo Katila; Lauri Toivonen
Related Documents :
17175045 - Cardiovascular magnetic resonance findings in typical versus atypical forms of the acut...
616055 - Effect of sodium salicylate and acetylsalicylic acid on epicardial st-segment elevation...
22720015 - Down-regulation of replication factor c-40 (rfc40) causes chromosomal missegregation in...
2756875 - Prognostic significance of st potentials determined by body surface mapping in inferior...
19332195 - Aldosterone and long-term outcome after myocardial infarction: a substudy of the french...
10549845 - Myocardial revascularisation after acute myocardial infarction.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Annals of medicine     Volume:  34     ISSN:  0785-3890     ISO Abbreviation:  Ann. Med.     Publication Date:  2002  
Date Detail:
Created Date:  2002-07-10     Completed Date:  2002-12-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8906388     Medline TA:  Ann Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  120-9     Citation Subset:  IM    
Affiliation:
Division of Cardiology, Helsinki University Central Hospital, Finland. hahannin@sci.fi
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Body Surface Potential Mapping / instrumentation,  methods*
Case-Control Studies
Coronary Artery Disease / diagnosis,  physiopathology*
Echocardiography, Stress* / methods
Exercise Test
Female
Heart Conduction System / physiopathology*
Humans
Logistic Models
Male
Middle Aged
Myocardial Ischemia / diagnosis,  physiopathology*
Research Design
Sensitivity and Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The enigma of fetal alcohol neurotoxicity.
Next Document:  Differences in the activation patterns between sustained and self-terminating episodes of human vent...