| Feasibility of tissue magnetic resonance imaging: a pilot study in comparison with tissue Doppler imaging and invasive measurement. | |
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MedLine Citation:
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PMID: 15808772 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: This research was intended to determine the feasibility of tissue magnetic resonance (MR) imaging in comparison with tissue Doppler imaging and its potential implications for the estimation of filling pressure, in comparison with invasive measurement. BACKGROUND: Evaluation of diastolic function using MR imaging is commonly confined to the study of transmitral flow. However, transmitral flow is unreliable for the estimation of left ventricular (LV) filling pressures in hypertrophy and normal systolic function. Normalizing early mitral velocity (E) for the influence of myocardial relaxation by combining E with early diastolic mitral septal tissue velocity (Ea) provides better Doppler estimates of filling pressures. METHODS: Eighteen patients with hypertensive heart disease (LV mass index: 114 +/- 21 g/m(2)), absence of valvular regurgitation, and with normal or mildly reduced systolic function (LV ejection fraction: 57.6 +/- 6.5%) referred for cardiac catheterization, underwent consecutive measurement of mitral flow and septal tissue velocities with phase-contrast MR and Doppler. These data were compared with mean pulmonary capillary wedge pressure (PCWP). RESULTS: There was a strong relation between MR (11.6 +/- 4.3) and Doppler-assessed (12.1 +/- 3.5) E/Ea (95% confidence interval of -1.5 to 0.5) (r = 0.89, p < 0.0001). In addition, E/Ea related strongly to invasively measured PCWP (MR: r = 0.80, p < 0.0001 and Doppler: r = 0.85, p < 0.0001). CONCLUSIONS: Tissue MR imaging is a feasible method to assess Ea. Combining E and Ea allowed similar estimation of filling pressure by MR and Doppler, in good agreement with invasive measurement. The potential confounding effect of valvular regurgitation needs further study. |
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Authors:
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Bernard P Paelinck; Albert de Roos; Jeroen J Bax; Johan M Bosmans; Rob J van Der Geest; Dominique Dhondt; Paul M Parizel; Christiaan J Vrints; Hildo J Lamb |
Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of the American College of Cardiology Volume: 45 ISSN: 0735-1097 ISO Abbreviation: J. Am. Coll. Cardiol. Publication Date: 2005 Apr |
Date Detail:
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Created Date: 2005-04-05 Completed Date: 2005-04-22 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8301365 Medline TA: J Am Coll Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 1109-16 Citation Subset: AIM; IM |
Affiliation:
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Department of Cardiology, University Hospital Antwerp, Wilrijkstraat 10, 2650 Edegem, Antwerp, Belgium. Bernard.Paelinck@uza.be |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Flow Velocity Coronary Circulation Echocardiography, Doppler / methods Feasibility Studies Female Heart Catheterization Heart Diseases / diagnosis*, pathology, physiopathology*, ultrasonography Humans Magnetic Resonance Imaging / methods* Male Middle Aged Mitral Valve / physiology Pilot Projects Predictive Value of Tests Pulmonary Wedge Pressure Pulsatile Flow Ventricular Dysfunction, Left / diagnosis, pathology, physiopathology, ultrasonography |
| Comments/Corrections | |
Erratum In:
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J Am Coll Cardiol. 2005 May 17;45(10):1737 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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