Document Detail


Feasibility study of an ultrasound contrast agent (levovist) in color Doppler imaging of liver neoplasms.
MedLine Citation:
PMID:  12903818     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to determine the efficacy of using an ultrasound contrast agent (levovist) to enhance the color Doppler imaging of liver neoplasms. Thirty patients with hepatic tumors were enrolled in this study. After intravenous administration of levovist, the color Doppler signals of normal hepatic vessels were enhanced. In various hepatic tumors, the different patterns of tumor vascularity were observed, which had not been demonstrated in conventional non-contrast color Doppler imaging. In 11 of 16 patients with hepatocarcinoma, additional color Doppler signals were observed in the central part of the tumors. On the contrary, 3 patients with metastatic liver lesions the enhanced color Doppler signals appear only at the peripheral of tumors. A typical rim-like color enhancement was seen in 2 of the 3 cases. In six patients with hepatic hemangiomas contrast-enhanced color Doppler imaging demonstrated the blood vessels at the margin of the neoplasms. Contrast-enhanced color Doppler imaging improves the visualization of the hepatic neoplasm vascularity. This technique holds great promise for detecting small liver tumors and differentiating hepatic neoplasms.
Authors:
Y Jiang; Q Dai; J Liu; J Zhang; X Chang; S Cai; L Tan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chinese medical sciences journal = Chung-kuo i hsüeh k'o hsüeh tsa chih / Chinese Academy of Medical Sciences     Volume:  14     ISSN:  1001-9294     ISO Abbreviation:  Chin. Med. Sci. J.     Publication Date:  1999 Sep 
Date Detail:
Created Date:  2003-08-07     Completed Date:  2003-10-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9112559     Medline TA:  Chin Med Sci J     Country:  China    
Other Details:
Languages:  eng     Pagination:  167-9     Citation Subset:  IM    
Affiliation:
Department of Diagnostic Ultrasound, Peking Union Medical College Hospital, CAMS & PUMC, Beijing 100730.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Carcinoma, Hepatocellular / ultrasonography*
Contrast Media / administration & dosage
Feasibility Studies
Female
Humans
Image Enhancement
Injections, Intravenous
Liver Neoplasms / ultrasonography*
Male
Middle Aged
Polysaccharides / diagnostic use*
Ultrasonography, Doppler, Color*
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Polysaccharides; 127279-08-7/SHU 508

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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