| Feasibility study of sutureless distal coronary anastomoses with degradable Y-shunt and tissue adhesives in a porcine off-pump model. | |
| | |
MedLine Citation:
|
PMID: 17670681 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
|
The purpose of this study was to examine the feasibility of the combined use of intraluminal biodegradable shunts and surgical adhesives for sutureless distal coronary anastomosis. Eighteen LITA-LAD anastomoses were created in a porcine beating heart model. In group I (n=9) a custom-made silicone Y-shunt provided internal stability, while three different adhesives, N-butyl-2-cyanoacrylate-glue (CYAC); albumin-glutaraldehyde-glue (AG); fibrin-glue (FIB), were applied externally. In group II (n=9) biodegradable polydioxanone (PDS) shunts were used. All anastomoses were examined intraoperatively by flow measurement, blood leakage was quantified and physical strength was tested. In all pigs anastomoses could be created successfully at first attempt, but anastomotic leaks requiring additional sutures occurred in 6 animals. LITA-flow significantly decreased in both groups. A patency rate of 89.9% (8/9) was found in group I while it was 66.6% (5/9) in group II. The lowest amount of blood-loss was measured when CYAC adhesive was used while tensile strength was lowest in the FIB-anastomoses. Preliminarily we could demonstrate the feasibility of performing sutureless distal coronary anastomosis by means of a combination of adhesives and temporary intraluminal shunts. PDS-shunts, however, resulted in a high graft-occlusion rate, so that potentially less thrombotic materials need to be investigated. |
| | |
Authors:
|
Jens Wippermann; Christo Konstas; Thorsten Wahlers; Johannes M Albes |
Publication Detail:
|
Type: Journal Article Date: 2006-08-24 |
Journal Detail:
|
Title: Interactive cardiovascular and thoracic surgery Volume: 5 ISSN: 1569-9285 ISO Abbreviation: Interact Cardiovasc Thorac Surg Publication Date: 2006 Dec |
Date Detail:
|
Created Date: 2007-08-02 Completed Date: 2007-08-08 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101158399 Medline TA: Interact Cardiovasc Thorac Surg Country: England |
Other Details:
|
Languages: eng Pagination: 676-9 Citation Subset: - |
Affiliation:
|
Department of Cardiothoracic Surgery, University Hospital Cologne, Kerpener Str. 62, 50937 Cologne, Germany. jens.wippermann@uk-koeln.de |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Introduction of transesophageal electrocardiography to surgery for continuous atrial fibrillation.
Next Document: Preliminary experience with the mini-extracorporeal circulation system (Medtronic resting heart syst...