Document Detail


Feasibility study of a randomized controlled trial of a telephone-delivered problem-solving-occupational therapy intervention to reduce participation restrictions in rural breast cancer survivors undergoing chemotherapy.
MedLine Citation:
PMID:  20821373     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Breast cancer patients receiving adjuvant chemotherapy often experience functional effects of treatment that limit participation in life activities. The purpose of this study was to examine the feasibility of conducting a randomized controlled trial (RCT) of a novel intervention for these restrictions, determine acceptability of the intervention, and preliminarily assess its effects.
METHODS: A pilot RCT of a telephone-delivered Problem-solving and Occupational Therapy intervention (PST-OT) to improve participation restrictions in rural breast cancer patients undergoing chemotherapy. Thirty-one participants with Stages 1-3 breast cancer were randomized to 6 weekly sessions of PST-OT (n = 15) and usual care (n = 16). The primary study outcome was the feasibility of conducting the trial. Secondary outcomes were functional, quality of life and emotional status as assessed at baseline, 6 and 12 weeks.
RESULTS: Of 46 patients referred 31 were enrolled (67% recruitment rate), of which 6 participants withdrew (81% retention rate). Twenty-four participants completed all study-related assessments (77%). Ninety-two percent of PST-OT participants were highly satisfied with the intervention, and 92% reported PST-OT to be helpful/very helpful for overcoming participation restrictions. Ninety-seven percent of planned PST-OT treatment sessions were completed. Completion rates for PST-OT homework tasks were high. Measures of functioning, quality of life, and emotional state favored the PST-OT condition.
CONCLUSION: This pilot study suggests that an RCT of the PST-OT intervention is feasible to conduct with rural breast cancer patients undergoing adjuvant chemotherapy and that PST-OT may have positive effects on function, quality of life, and emotional state.
Authors:
Mark T Hegel; Kathleen D Lyons; Jay G Hull; Peter Kaufman; Laura Urquhart; Zhongze Li; Tim A Ahles
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural     Date:  2010-09-05
Journal Detail:
Title:  Psycho-oncology     Volume:  20     ISSN:  1099-1611     ISO Abbreviation:  Psychooncology     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-09-28     Completed Date:  2012-02-01     Revised Date:  2014-09-21    
Medline Journal Info:
Nlm Unique ID:  9214524     Medline TA:  Psychooncology     Country:  England    
Other Details:
Languages:  eng     Pagination:  1092-101     Citation Subset:  IM    
Copyright Information:
2010 John Wiley & Sons, Ltd.
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MeSH Terms
Descriptor/Qualifier:
Activities of Daily Living / psychology
Antineoplastic Agents / adverse effects,  therapeutic use
Anxiety / etiology,  psychology
Breast Neoplasms / drug therapy,  psychology,  rehabilitation*
Depression / etiology,  psychology
Exercise Therapy / psychology
Feasibility Studies
Female
Humans
Middle Aged
Occupational Therapy / methods*
Patient Compliance
Psychiatric Status Rating Scales
Rural Population
Survivors / psychology*
Telephone
Grant Support
ID/Acronym/Agency:
P30 CA023108/CA/NCI NIH HHS; R03 CA124200/CA/NCI NIH HHS; R03 CA124200-02/CA/NCI NIH HHS; R03CA124200/CA/NCI NIH HHS
Chemical
Reg. No./Substance:
0/Antineoplastic Agents
Comments/Corrections
Comment In:
Aust Occup Ther J. 2013 Feb;60(1):72-4   [PMID:  23414193 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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