| Feasibility of semi-quantitative assessment of left ventricular contractile reserve in dilated cardiomyopathy. | |
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MedLine Citation:
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PMID: 22407437 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: We and others have shown previously that left ventricular (LV) contractile reserve assessed quantitatively by high-dose dobutamine stress-echocardiography (DSE) has prognostic implications in patients with dilated cardiomyopathy. PURPOSE: To assess the feasibility of semi-quantitative assessment of LV contractile reserve by differently skilled operators in patients with dilated cardiomyopathy. METHODS: High-dose DSE was performed in 63 consecutive patients, mean age 50 ± 10 years and ejection fraction (EF) 19 ± 8%. LVEF was calculated 1) using Simpson's biplane formula, and 2) semi-quantitatively (5% increments) by novice and experienced echocardiographers, and by a DSE expert. Patients were considered to have preserved LV contractile reserve if LVEF dobutamine-induced change was ≥5%. RESULTS: Twenty-seven (45.8%) patients died during the 5-year follow-up. The feasibility of the assessment was 89%, 94%, and 98% for novice and experienced readers and DSE expert, respectively. Kaplan-Meier analysis showed that LV contractile reserve assessed semi-quantitatively by DSE expert and experienced reader achieved the best prognostic separation (log rank 19.63 and 18.99, respectively, p < 0.001 for both), followed by quantitative assessment (log rank 9.76, p = 0.0018) and assessment by novice reader (log rank 8.76, p = 0.012). Areas under the curves were similar for quantitative and semi-quantitative assessment of LV contractile reserve. CONCLUSIONS: Our data indicate that semi-quantitative assessment of LV contractile reserve is feasible by differently skilled operators. © 2012 Wiley Periodicals, Inc. J Clin Ultrasound, 2012; |
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Authors:
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Petar Otasevic; Nebojsa Tasic; Radoslav Vidakovic; Srdjan Boskovic; Djordje Radak; Bosko Djukanovic; Lazar Angelkov; Nada Kostic; Zorica Caparevic; Zorana Vasiljevic-Pokrajcic |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-3-10 |
Journal Detail:
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Title: Journal of clinical ultrasound : JCU Volume: - ISSN: 1097-0096 ISO Abbreviation: - Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-3-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401663 Medline TA: J Clin Ultrasound Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Wiley Periodicals, Inc. |
Affiliation:
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"Dr Aleksandar D. Popovic" Cardiovascular Research Center, Dedinje Cardiovascular Institute and Belgrade University Medical School, Belgrade, Serbia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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