Document Detail

Feasibility and preliminary effectiveness of a novel mobility training intervention in infants and toddlers with cerebral palsy.
MedLine Citation:
PMID:  22670679     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To design a novel mobility training intervention incorporating infant motor learning and neurorehabilitation principles and investigate its feasibility, tolerability and effect on motor development in toddlers with cerebral palsy (CP).
METHODS: A single-subject research design with repeated measures during 6-week baseline and intervention phases and after treatment withdrawal was used. Five participants attended therapy utilizing novel dynamic weight assistance technology, which allowed practice of motor skills beyond participants' current abilities.
RESULTS: Average attendance and engagement rates exceeded 90%. Gains in gross motor function were observed after treatment that exceeded the expected rate in four of the five participants. Rates of motor development during treatment were 10.8, 3.8, 7.0, 15.1, and 0.3 times greater than during baseline for the five participants, respectively.
CONCLUSIONS: This intervention was tolerated and demonstrated the potential to alter the trajectory of motor development in CP, providing proof of concept for further investigation.
Laura A Prosser; Laurie B Ohlrich; Lindsey A Curatalo; Katharine E Alter; Diane L Damiano
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, N.I.H., Intramural     Date:  2012-06-06
Journal Detail:
Title:  Developmental neurorehabilitation     Volume:  15     ISSN:  1751-8431     ISO Abbreviation:  Dev Neurorehabil     Publication Date:  2012  
Date Detail:
Created Date:  2012-07-04     Completed Date:  2012-12-04     Revised Date:  2013-07-12    
Medline Journal Info:
Nlm Unique ID:  101304394     Medline TA:  Dev Neurorehabil     Country:  England    
Other Details:
Languages:  eng     Pagination:  259-66     Citation Subset:  IM    
Division of Rehabilitation Medicine, The Children's Hospital of Philadelphia, PA 19104, USA.
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MeSH Terms
Cerebral Palsy / physiopathology,  rehabilitation*
Child Development / physiology*
Child, Preschool
Feasibility Studies
Motor Skills / physiology*
Pilot Projects
Treatment Outcome
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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