| Feasibility of peripheral contrast-enhanced magnetic resonance angiography at 3.0 Tesla with a hybrid technique: comparison with digital subtraction angiography. | |
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MedLine Citation:
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PMID: 18708858 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To prospectively determine feasibility and diagnostic accuracy of 3D contrast-enhanced MR-angiography (CE-MRA) at 3.0 tesla (T) in patients with peripheral arterial occlusive disease. Digital subtraction angiography (DSA) was used as reference standard. MATERIAL AND METHODS: Thirty consecutive patients with suspected peripheral arterial occlusive disease were examined on a 3.0 T MR system by using the integrated whole body coil. A 4-station examination protocol in hybrid technique was chosen, containing 2 gadodiamide injections, the first one for imaging the calf and foot arteries (single-step technique) and the second injection for the visualization of the aortoiliacal and femoral arteries (bolus-chase MRA). All patients underwent DSA within the following 48 hours. The arterial tree of each leg was divided in 15 segments and 4 anatomic regions (iliacal, femoral, popliteal/proximal calf, distal calf/foot). Two radiologists analyzed the MR-images with regard to image quality, grade of stenosis, and venous overlap. DSA-images were analyzed by 2 radiologists in consensus with regard to the stenosis grade. RESULTS: Eight hundred eighty-five and 884 of 889 arterial segments at CE-MRA were rated with excellent or good diagnostic image quality by observer 1 and observer 2, respectively. In only 3 segments image quality was affected by venous contamination. Sensitivity of CE-MRA for determination of relevant arterial stenoses (50%-99%) and occlusions--as compared with DSA--was 95.3% (both observer) and specificity was 98.5% and 97.8% for observer 1 and observer 2, respectively. CONCLUSION: Peripheral hybrid CE-MRA at 3.0 T is feasible and proved to be reliable at depiction of stenoses and occlusions of the whole pelvic and lower leg arterial system. |
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Authors:
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Frank Berg; Christopher Bangard; Henning Bovenschulte; Martin Hellmich; Marco Nijenhuis; Klaus Lackner; Axel Gossmann |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article |
Journal Detail:
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Title: Investigative radiology Volume: 43 ISSN: 1536-0210 ISO Abbreviation: Invest Radiol Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-08-18 Completed Date: 2008-10-30 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0045377 Medline TA: Invest Radiol Country: United States |
Other Details:
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Languages: eng Pagination: 642-9 Citation Subset: IM |
Affiliation:
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Department of Radiology, University of Cologne, Cologne, Germany. frank.berg@uk-koeln.de |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Angiography, Digital Subtraction Contrast Media* Feasibility Studies Female Humans Image Enhancement / methods* Imaging, Three-Dimensional / methods* Magnetic Resonance Angiography / methods* Male Middle Aged Peripheral Vascular Diseases / diagnosis* Reproducibility of Results Sensitivity and Specificity Subtraction Technique* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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