Document Detail


Feasibility of in vivo pressure measurement using a pressure-tip catheter via transventricular puncture.
MedLine Citation:
PMID:  20400891     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pressure-tip catheters (PTCs) are used to evaluate ventricular mechanics during surgical repair of congenital heart disease in children. Studies in infants require miniaturized sensors. We compared the safety and accuracy of a 2-Fr ultraminiature PTC with a 5-Fr PTC. In 10 piglets (weight 19-22 kg), a 5-Fr PTC was inserted through a 3-mm apical puncture with a #11 blade. A 20-gauge angiocatheter was inserted using a separate site. A 2-Fr PTC was threaded through the angiocatheter lumen. The angiocatheter was withdrawn, leaving the 2-Fr PTC within the left ventricle (LV). Left ventricular pressure (LVP) changes were measured during three inferior vena caval occlusions. Reliability coefficients demonstrated correlation between the 2-Fr PTC and 5-Fr PTC for LV end-diastolic pressure (0.90-0.95), peak LVP (0.92-0.99), and the maximal (0.87-0.93) and minimal (0.89-0.94) first derivatives of LVP. Bland-Altman analysis demonstrated agreement for all variables. Blood loss was trivial with pressure manipulation and catheter placement and removal. Pressure measurements using the 2-Fr PTC were accurate and comparable with those from the 5-Fr PTC. Transventricular placement of a 2-Fr PTC is feasible and should allow evaluation of ventricular mechanics during surgical repair of congenital heart disease.
Authors:
Robert G Gray; Santos E Cabreriza; T Alexander Quinn; Alan D Weinberg; Henry M Spotnitz
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  ASAIO journal (American Society for Artificial Internal Organs : 1992)     Volume:  56     ISSN:  1538-943X     ISO Abbreviation:  ASAIO J.     Publication Date:    2010 May-Jun
Date Detail:
Created Date:  2010-05-04     Completed Date:  2010-08-10     Revised Date:  2014-09-18    
Medline Journal Info:
Nlm Unique ID:  9204109     Medline TA:  ASAIO J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  194-9     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Catheterization
Child
Feasibility Studies
Heart Defects, Congenital / surgery*
Heart Ventricles / surgery
Humans
Infant
Pressure
Punctures
Grant Support
ID/Acronym/Agency:
R01 HL080152/HL/NHLBI NIH HHS; R01 HL080152-03/HL/NHLBI NIH HHS; R01-HL48109/HL/NHLBI NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Computational fluid dynamics analysis of thrombosis potential in left ventricular assist device drai...
Next Document:  Biocompatibility Investigation of Polyethylene Glycol and Alginate-Poly-l-Lysine for Islet Encapsula...