| Feasibility of in vivo pressure measurement using a pressure-tip catheter via transventricular puncture. | |
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MedLine Citation:
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PMID: 20400891 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pressure-tip catheters (PTCs) are used to evaluate ventricular mechanics during surgical repair of congenital heart disease in children. Studies in infants require miniaturized sensors. We compared the safety and accuracy of a 2-Fr ultraminiature PTC with a 5-Fr PTC. In 10 piglets (weight 19-22 kg), a 5-Fr PTC was inserted through a 3-mm apical puncture with a #11 blade. A 20-gauge angiocatheter was inserted using a separate site. A 2-Fr PTC was threaded through the angiocatheter lumen. The angiocatheter was withdrawn, leaving the 2-Fr PTC within the left ventricle (LV). Left ventricular pressure (LVP) changes were measured during three inferior vena caval occlusions. Reliability coefficients demonstrated correlation between the 2-Fr PTC and 5-Fr PTC for LV end-diastolic pressure (0.90-0.95), peak LVP (0.92-0.99), and the maximal (0.87-0.93) and minimal (0.89-0.94) first derivatives of LVP. Bland-Altman analysis demonstrated agreement for all variables. Blood loss was trivial with pressure manipulation and catheter placement and removal. Pressure measurements using the 2-Fr PTC were accurate and comparable with those from the 5-Fr PTC. Transventricular placement of a 2-Fr PTC is feasible and should allow evaluation of ventricular mechanics during surgical repair of congenital heart disease. |
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Authors:
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Robert G Gray; Santos E Cabreriza; T Alexander Quinn; Alan D Weinberg; Henry M Spotnitz |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: ASAIO journal (American Society for Artificial Internal Organs : 1992) Volume: 56 ISSN: 1538-943X ISO Abbreviation: ASAIO J. Publication Date: 2010 May-Jun |
Date Detail:
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Created Date: 2010-05-04 Completed Date: 2010-08-10 Revised Date: 2011-08-01 |
Medline Journal Info:
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Nlm Unique ID: 9204109 Medline TA: ASAIO J Country: United States |
Other Details:
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Languages: eng Pagination: 194-9 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Division of Pediatric Cardiology, The University of Utah, Salt Lake City, Utah, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Catheterization Child Feasibility Studies Heart Defects, Congenital / surgery* Heart Ventricles / surgery Humans Infant Pressure Punctures |
| Grant Support | |
ID/Acronym/Agency:
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R01 HL080152-03/HL/NHLBI NIH HHS; R01-HL48109/HL/NHLBI NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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