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Feasibility Of Administering Adjuvant Chemotherapy Of Pemetrexed Followed By Pemetrexed/oxaliplatin Immediately Post-VATS In Patients With Completely Resected NSCLC.
MedLine Citation:
PMID:  22263005     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Non-small cell lung cancer (NSCLC) accounts for the largest number of cancer deaths annually, worldwide. It seems reasonable to test a less toxic regimen also in early stages after complete (R0) resection of the tumor, where reduced toxicities might improve the feasibility of drug delivery, compliance and the convenience of treatment for the patient and hence perhaps improve survival. The main purpose of this phase II trial is to evaluate the clinical feasibility-in terms of patients without dose limiting toxicities or premature treatment withdrawal or death-of administering adjuvant chemotherapy of pemetrexed followed by pemetrexed/oxaliplatin immediately post-VATS (video-assisted thoracic surgery) in patients with completely resected NSCLC.
Authors:
Jianxing He; Wenlong Shao; Shuben Li; Manyin Chen; Hanzhang Chen; Jun Liu; Wei Wang; Yuan Qiu; Daoyuan Wang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of thoracic disease     Volume:  1     ISSN:  2072-1439     ISO Abbreviation:  J Thorac Dis     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2012-01-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101533916     Medline TA:  J Thorac Dis     Country:  China    
Other Details:
Languages:  eng     Pagination:  55-62     Citation Subset:  -    
Affiliation:
Department of Cardiothoracic Surgery, the First Affiliated Hospital of Guangzhou Medical College; Guangzhou Research Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease, Guangzhou, PR China.
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