Document Detail

Fear reactivity to bodily sensations among heavy smokers and nonsmokers.
MedLine Citation:
PMID:  18540783     Owner:  NLM     Status:  MEDLINE    
Individuals who smoke are more likely to experience panic attacks and develop panic disorder than those in the general population. One possible explanation is that smokers may experience a heightened fear response to somatic disturbances. To date, few laboratory studies have tested this hypothesis directly. The present study examined 24 adult heavy smokers (10 females) in 12-hr nicotine withdrawal and 24 adult nonsmokers (12 females) on subjective and physiological reactivity to a 4-min carbon dioxide rebreathing challenge. Results indicate that, despite an attenuated acceleration in respiration during the challenge, smokers experienced a significantly greater increase in self-reported panic symptoms than nonsmokers. In addition, smokers reported significantly greater trait levels of suffocation fear prior to the challenge. Findings are discussed with respect to the role of smoking in panic vulnerability.
Kenneth Abrams; Michael J Zvolensky; Lindsey Dorflinger; Andrea Galatis; Melissa Blank; Thomas Eissenberg
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Experimental and clinical psychopharmacology     Volume:  16     ISSN:  1064-1297     ISO Abbreviation:  Exp Clin Psychopharmacol     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-06-10     Completed Date:  2008-11-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9419066     Medline TA:  Exp Clin Psychopharmacol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  230-9     Citation Subset:  IM    
Department of Psychology, Carleton College, Northfield, MN 55057, USA.
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MeSH Terms
Alcoholism / psychology
Asphyxia / psychology
Carbon Dioxide / diagnostic use
Data Interpretation, Statistical
Fear / drug effects,  psychology*
Heart Rate / drug effects,  physiology
Neuropsychological Tests
Panic / physiology
Respiratory Mechanics
Sensation / drug effects,  physiology*
Smoking / psychology*
Substance Withdrawal Syndrome / psychology
Tidal Volume / physiology
Tobacco Use Disorder / psychology
Reg. No./Substance:
124-38-9/Carbon Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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