Document Detail

Fe(III)-EDTA complex as iron fortification.
MedLine Citation:
PMID:  406778     Owner:  NLM     Status:  MEDLINE    
Fe(III)-EDTA as iron fortification presents several advantages over the other iron salts previously used including ferrous sulfate. This iron compound exchange completely with vegetable food iron in the lumen of the gut but with the characteristics that the absorption from both, extrinsic and intrinsic food iron, is higher than that expected from other iron salfs. The comparison between the iron absorption from Fe(III)-EDTA and ferrous sulfate as iron fortification indicates that the absorption form EDTA is about twice as high than that observed from ferrous sulfate. The data indicates that only 10 to 15 mg of iron as Fe(III)-EDTA as iron fortification would be necessary to prevent iron deficiency anemia in population relying their subsistence of vegetable food only and free of parastic infection producing blood loss.
M Layrisse; C Martínez-Torres
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  30     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1977 Jul 
Date Detail:
Created Date:  1977-08-12     Completed Date:  1977-08-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1166-74     Citation Subset:  AIM; IM    
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MeSH Terms
Ascorbic Acid
Edetic Acid / analogs & derivatives*,  metabolism
Ferric Compounds
Ferrous Compounds
Food, Fortified
Hemoglobins / metabolism
Iron* / metabolism
Transferrin / metabolism
Zea mays
Reg. No./Substance:
0/Ferric Compounds; 0/Ferrous Compounds; 0/Hemoglobins; 11096-37-0/Transferrin; 50-81-7/Ascorbic Acid; 60-00-4/Edetic Acid; 7439-89-6/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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