Document Detail


Fe(III)-EDTA complex as iron fortification. Further studies.
MedLine Citation:
PMID:  107784     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The data presented confirm the advantages of Fe(III)-EDTA as a salt for iron fortification. This iron compound exchanges completely with intrinsic wheat iron in the lumen of the gut. The iron absorption data from this salt tested with six different food vehicles compared with the absorption of ferrous sulfate administered with the same vehicles indicate that while the mean absorption from ferrous sulfate varies from 2 to 30% according to the food vehicle mixed with the salt, the absorption from Fe(III)-EDTA remains practically the same. Apparently, the iron absorption from Fe(III)-EDTA complex is slightly or not affected by the presence of vegetable foods or milk. All these data suggest that only a small amount of iron from this salt, about 10 mg/day, would be necessary to prevent iron deficiency anemia even in those populations relying for their subsistence on vegetable food only.
Authors:
C Martínez-Torres; E L Romano; M Renzi; M Layrisse
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  32     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1979 Apr 
Date Detail:
Created Date:  1979-06-29     Completed Date:  1979-06-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  809-16     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Absorption
Anemia, Hypochromic / prevention & control
Dietary Carbohydrates
Edetic Acid*
Female
Ferric Compounds / metabolism
Ferritins / blood
Ferrous Compounds / metabolism
Food, Fortified*
Hemoglobins / metabolism
Humans
Iron Chelating Agents / metabolism*
Male
Structure-Activity Relationship
Sulfates
Transferrin / metabolism
Triticum
Chemical
Reg. No./Substance:
0/Dietary Carbohydrates; 0/Ferric Compounds; 0/Ferrous Compounds; 0/Hemoglobins; 0/Iron Chelating Agents; 0/Sulfates; 11096-37-0/Transferrin; 60-00-4/Edetic Acid; 9007-73-2/Ferritins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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