Document Detail

Favourable neurological outcomes following delivery room cardiopulmonary resuscitation of infants < or = 750 g at birth.
MedLine Citation:
PMID:  10723685     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To study short- and long-term outcomes of infants < or = 750 g birthweight who received cardiopulmonary resuscitation (CPR) in the delivery room. METHODOLOGY: A retrospective analysis of all inborn live births < or = 750 g birthweight from 1990 to 1996. Cardiopulmonary resuscitation was defined as positive pressure ventilation via an endotracheal tube and chest compressions. Univeriate analysis were conducted comparing patients according to the use of CPR or positive pressure ventilation alone. RESULTS: Cardiopulmonary resuscitation was administered to 16 infants: four received chest compressions only and 12 also received adrenaline. Cardiopulmonary resuscitation recipients had significantly lower Apgar scores at both 1 and 5 min, and had delayed onset of spontaneous respiration (P < 0.01). Seven patients died, and eight of nine survivors were free of major neurodevelopmental abnormalities at follow up. All CPR recipients with a 5 min Apgar score of < or = 5 and delayed onset of spontaneous respiration beyond 5 min had poor outcomes. CONCLUSION: Contrary to the majority of published evidence, delivery room CPR in our extremely small infants was not associated with a high risk of severe neurodevelopmental disability.
R P Jankov; E V Asztalos; M B Skidmore
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of paediatrics and child health     Volume:  36     ISSN:  1034-4810     ISO Abbreviation:  J Paediatr Child Health     Publication Date:  2000 Feb 
Date Detail:
Created Date:  2000-04-04     Completed Date:  2000-04-04     Revised Date:  2007-09-24    
Medline Journal Info:
Nlm Unique ID:  9005421     Medline TA:  J Paediatr Child Health     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  19-22     Citation Subset:  IM    
Newborn Intensive Care Unit, Women's College Hospital, University of Toronto, Ontario, Canada.
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MeSH Terms
Apgar Score
Brain Diseases / epidemiology
Cardiopulmonary Resuscitation*
Delivery, Obstetric
Infant, Newborn
Infant, Very Low Birth Weight*
Outcome Assessment (Health Care)*
Positive-Pressure Respiration
Retrospective Studies
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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