| Fatty acids in serum and diet - a canonical correlation analysis among toddlers. | |
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MedLine Citation:
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PMID: 22066932 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Fatty acid concentrations in blood are potential biomarkers of dietary fat intake, but methodological studies among children are scarce. The large number of fatty acids and their complex interrelationships pose a special challenge in research on fatty acids. Our target was to assess the interrelationships between the total fatty acid profiles in diet and serum of young children. The study subjects were healthy control children from the birth cohort of the Type 1 Diabetes Prediction and Prevention Study. A 3-day food record and a frozen serum sample were available from 135 children at the age of 1 year, from 133 at 2 years, and from 92 at 3 years. The relationship between dietary and serum fatty acid profiles was analysed using canonical correlation analysis. The consumption of fatty milk correlated positively with serum fatty acids, pentadecanoic acid, palmitic acid and conjugated linoleic acid (CLA) at all ages. Correlations between dietary and serum eicosapentaenoic and/or docosahexaenoic acid were observed at 2 and 3 years of age. Serum linoleic acid was positively associated with the consumption of infant formula at the age of 1 year, and with the consumption of vegetable margarine at 2 and 3 years. The results indicate a high quality of the 3-day food records kept by parents and other caretakers of the children, and suitability of non-fasting, un-fractioned serum samples for total fatty acid analyses. The correlation between intake of milk fat and serum proportion of CLA is a novel finding. |
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Authors:
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Liisa Uusitalo; Jaakko Nevalainen; Irma Salminen; Marja-Leena Ovaskainen; Carina Kronberg-Kippilä; Suvi Ahonen; Sari Niinistö; Georg Alfthan; Olli Simell; Jorma Ilonen; Riitta Veijola; Mikael Knip; Suvi M Virtanen |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-8 |
Journal Detail:
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Title: Maternal & child nutrition Volume: - ISSN: 1740-8709 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-9 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101201025 Medline TA: Matern Child Nutr Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 Blackwell Publishing Ltd. |
Affiliation:
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School of Health Sciences, University of Tampere, 33014 Tampere, Finland Nutrition Unit, Department of Lifestyle and Participation, National Institute for Health and Welfare, 00271 Helsinki, Finland Statistics/Department of Social Research, University of Turku, 20014 Turku, Finland Disease Risk Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, 00271 Helsinki, Finland Hjelt Institute, University of Helsinki, 00014 Helsinki, Finland The Science Center of Pirkanmaa Hospital District, 33521 Tampere, Finland Department of Paediatrics, University of Turku, 20520 Turku, Finland Immunogenetics Laboratory, University of Turku, MediCity, 20520 Turku, Finland Department of Clinical Microbiology, University of Eastern Finland, Kuopio, Finland Department of Pediatrics, University of Oulu, 90014 Oulu, Finland Department of Pediatrics, Tampere University Hospital, 33521 Tampere, Finland Hospital for Children and Adolescents and Folkhälsan Research Center, University of Helsinki, 00014 Helsinki, Finland Department of Pediatrics, Tampere University Hospital, 33521 Tampere, Finland. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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