| Fatty acid profile and influence of oxythiamine on fatty acid content in Malassezia pachydermatis, Candida albicans and Saccharomyces cerevisiae. | |
| | |
MedLine Citation:
|
PMID: 22066764 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Malassezia pachydermatis and Candida albicans are fungi involved in the skin diseases and systemic infections. The therapy of such infections is difficult due to relapses and problems with pathogen identification. In our study, we compare the fatty acids profile of M. pachydermatis, C. albicans and S. cerevisiae to identify diagnostic markers and to investigate the effect of oxythiamine (OT) on the lipid composition of these species. Total fatty acid content is threefold higher in C. albicans and M. pachydermatis compared with S. cerevisiae. These two species have also increased level of polyunsaturated fatty acids (PUFA) and decreased content of monounsaturated fatty acids (MUFA). We noted differences in the content of longer chain (>18) fatty acids between studied species (for example a lack of 20 : 1 in S. cerevisiae and 22 : 0 in M. pachydermatis and C. albicans). OT reduces total fatty acids content in M. pachydermatis by 50%. In S. cerevisiae, OT increased PUFA whereas it decreased MUFA content. In C. albicans, OT decreased PUFA and increased MUFA and SFA content. The results show that the MUFA to PUFA ratio and the fatty acid profile could be useful diagnostic tests to distinguish C. albicans, M. pachydermatis and S. cerevisiae, and OT affected the lipid metabolism of the investigated species, especially M. pachydermatis. |
| | |
Authors:
|
Adam Tylicki; Magdalena Siemieniuk; Pawel Dobrzyn; Grazyna Ziolkowska; Magdalena Nowik; Urszula Czyzewska; Aleksandra Pyrkowska |
Related Documents
:
|
12610704 - Study of the acid-base properties of fulvic acid-like substances extracted from senesce... 18682364 - Body odour of monozygotic human twins: a common pattern of odorant carboxylic acids rel... 16737754 - Rapid characterization of microbial biodegradation pathways by ft-ir spectroscopy. 15875394 - H2s-induced reorganization of mixed monolayer of carboxylic derivatives on silver surface. 19356914 - Dietary linoleic acid has no effect on arachidonic acid, but increases n-6 eicosadienoi... 234254 - Metabolism and properties of 3-methoxy-4-hydroxyphenyl-pyruvate; a metabolite of dihydr... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-11-9 |
Journal Detail:
|
Title: Mycoses Volume: - ISSN: 1439-0507 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
|
Created Date: 2011-11-9 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8805008 Medline TA: Mycoses Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
© 2011 Blackwell Verlag GmbH. |
Affiliation:
|
Departament of Cytobiochemistry, Institute of Biology, University of Bialystok, Bialystok, Poland Departament of Biochemistry, Nencki Institute of Experimental Biology, Warsaw, Poland Department of Veterinary Microbiology, Institute of Biological Bases of Animal Diseases, University of Life Sciences in Lublin, Lublin, Poland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Fluoroquinolone resistance of Escherichia coli and Salmonella from healthy livestock and poultry in ...
Next Document: Diversity of extended-spectrum ?-lactamase-producing Enterobacteriaceae on hospital admission.