| Fatty acid consumption and metabolic syndrome components: the GOCADAN study. | |
| | |
MedLine Citation:
|
PMID: 18059206 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Fatty acids (FAs) have been related to changes in glucose and lipid metabolism. In this article, the authors assess the association between intake of specific FAs and components of the metabolic syndrome (MS) in adult Eskimos. A total of 691 Inupiat Eskimos (325 men and 366 women), aged 34 to 75 years, were examined as part of the Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) study. The investigation included a physical examination, blood pressure measurements, blood sampling under fasting conditions, 2-hour oral glucose tolerance test, and a personal interview including a validated food frequency questionnaire. Components of MS were defined according to the Third Report of the National Cholesterol Education Program Adult Treatment Panel criteria. Consumption of individual FAs showed associations with MS components. Long-chain omega-3 FAs, from fish and sea mammals, were associated with lower blood pressure, serum triglycerides, and 2-hour glucose and higher high-density lipoprotein cholesterol, fasting insulin, and homeostasis model assessment. Saturated fat consumption was associated with higher triglyceride levels and blood pressure. Trans-FA consumption was associated with higher blood pressure. Consumption of long-chain omega-3 FAs from marine sources may improve certain MS components, and thus may reduce risk for cardiovascular disease. High consumption of saturated FAs and trans-FAs may have an adverse effect on MS. |
| | |
Authors:
|
Sven O E Ebbesson; M Elizabeth Tejero; Elizabeth D Nobmann; Juan Carlos Lopez-Alvarenga; Lars Ebbesson; Terri Romenesko; Elizabeth A Carter; Helaine E Resnick; Richard B Devereux; Jean W MacCluer; Bennett Dyke; Sandra L Laston; Charlotte R Wenger; Richard R Fabsitz; Anthony G Comuzzie; Barbara V Howard |
Related Documents
:
|
15067836 - Relation of body mass index with lipid profile and blood pressure in young healthy stud... 8799626 - Pain intensity and blood pressure reactions during a cold pressor test in iddm patients. 20105046 - The effect of body fat, aging, and diabetes on vertical and shear pressure in and under... 6746846 - Serum cholesterol, other risk factors, and cardiovascular disease in a japanese cohort. 3850766 - Effect of chronic prazosin treatment on the cardiac function and electrolytes in failin... 11330886 - Risk assessment and treatment benefit in intensively treated hypertensive patients of t... |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
|
Title: Journal of the cardiometabolic syndrome Volume: 2 ISSN: 1559-4564 ISO Abbreviation: - Publication Date: 2007 |
Date Detail:
|
Created Date: 2007-12-06 Completed Date: 2008-03-25 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101284690 Medline TA: J Cardiometab Syndr Country: United States |
Other Details:
|
Languages: eng Pagination: 244-9 Citation Subset: IM |
Affiliation:
|
Norton Sound Health Corp, Nome, AK, USA. ffsoe@uaf.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Alaska / epidemiology Blood Glucose / metabolism Blood Pressure Fatty Acids, Omega-3 / administration & dosage*, blood* Female Humans Insulin Resistance Inuits / statistics & numerical data* Linear Models Lipids / blood Male Metabolic Syndrome X / blood*, epidemiology, ethnology* Middle Aged Nutrition Surveys Risk Factors Statistics, Nonparametric Waist-Hip Ratio |
| Grant Support | |
ID/Acronym/Agency:
|
M10RR0047-34/RR/NCRR NIH HHS; R01-HL064244/HL/NHLBI NIH HHS; U01 HL082458/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Blood Glucose; 0/Fatty Acids, Omega-3; 0/Lipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Can intensive statin therapy halt the progression of atherosclerosis? Recent evidence and potential ...
Next Document: Cardiovascular disease disparities in native Hawaiians.